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Changes in the availability of medications for opioid use disorder in prisons and jails in the United States during the COVID-19 pandemic.
Dadiomov, David; Trotzky-Sirr, Rebecca; Shooshtari, Andrew; Qato, Dima M.
  • Dadiomov D; Program on Medicines and Public Health, Titus Family Department of Clinical Pharmacy, University of Southern California School of Pharmacy, Los Angeles, CA, USA; Department of Health Services, Los Angeles County, CA, USA.
  • Trotzky-Sirr R; Department of Health Services, Los Angeles County, CA, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Shooshtari A; Program on Medicines and Public Health, Titus Family Department of Clinical Pharmacy, University of Southern California School of Pharmacy, Los Angeles, CA, USA.
  • Qato DM; Program on Medicines and Public Health, Titus Family Department of Clinical Pharmacy, University of Southern California School of Pharmacy, Los Angeles, CA, USA; Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles, California, USA. Electronic a
Drug Alcohol Depend ; 232: 109291, 2022 03 01.
Article in English | MEDLINE | ID: covidwho-1616457
ABSTRACT

BACKGROUND:

During the COVID-19 pandemic, federal agencies relaxed buprenorphine prescribing restrictions including for incarcerated individuals. The impact of COVID-19 on the supply of MOUD in U.S. prisons and jails is not known.

METHODS:

We used cross-sectional national monthly data from the IQVIA National Sales Perspective (NSP) for the total volume of medicines supplied to city, county and state prisons and jails and other types of institutional facilities in the U.S. We measured the total monthly supply (or volume) as extended units (EUs) for MOUDs overall and by type. We used interrupted time series analysis to evaluate changes in monthly volume of MOUDs in prisons and jails and other types of facilities (hospitals, clinics and long-term care) before (January 2018-February 2020) and during the COVID-19 (March 2020-October 2020) pandemic.

RESULTS:

The availability of MOUD in jails and prisons increased by 471.3% between January 2018 (52,784 EU) and October 2020 (333,226 EU). This increase was largely driven by increased volume of buprenorphine/naloxone and was not observed in other institutional facilities, including hospitals, clinics and long-term care, and. Specifically, the mean monthly volume of buprenorphine/naloxone at prisons/jails increased every month before the pandemic by 1860 EU (95% CI, 1110-2360). In March 2020, the mean volume of buprenorphine/naloxone increased by 81,930 EU (95% CI, 59,040-104,820) per month, followed by a significant increase of 24,010 EU (95% CI 19,530-28,490) per month during the pandemic vs before the pandemic.

CONCLUSION:

These findings may indicate increased availability of buprenorphine/naloxone, a safe and effective MOUD, in prisons and jails since the start of the COVID-19 pandemic in the U.S. despite previous barriers in its use.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Buprenorphine / COVID-19 / Opioid-Related Disorders Type of study: Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: North America Language: English Journal: Drug Alcohol Depend Year: 2022 Document Type: Article Affiliation country: J.drugalcdep.2022.109291

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Buprenorphine / COVID-19 / Opioid-Related Disorders Type of study: Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: North America Language: English Journal: Drug Alcohol Depend Year: 2022 Document Type: Article Affiliation country: J.drugalcdep.2022.109291