Covid-19 in a patient with Familial Hemophagocytic Lymphohistiocytosis in children.
Turk J Pediatr
; 63(6): 1103-1107, 2021.
Article
in English
| MEDLINE | ID: covidwho-1622999
ABSTRACT
BACKGROUND:
Based on the information obtained so far, COVID- 19 is relatively mild in children. We will present a 6-month-old male patient infected with COVID -19 in April 2020, while receiving HLH 2004 chemotherapy protocol with the diagnosis of familial (Genetic / Primary) Hemophagocytic Lymphohistiocytosis (HLH). CASE Herein we present a case accompanied by a defective perforin gene defect in the primary HLH pathogenesis, Covid-19 infection with the presence of fever and hyperferritinemia, which was evaluated in favor of reactivation and the patient was given both the HLH-2004 chemotherapy protocol treatment and COVID -19 therapy as recommended by the guidelines. Our patient improved clinically and in terms of laboratory test results at the end of the 15 th < /sup > day of hospitalization and was discharged.CONCLUSIONS:
It should be remembered that COVID-19 can be seen with different clinical manifestations in the pediatric age group, and COVID-19 tests should be recommended, especially in children with immunosuppression and fever.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Lymphohistiocytosis, Hemophagocytic
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Experimental Studies
/
Prognostic study
Limits:
Child
/
Humans
/
Infant
/
Male
Language:
English
Journal:
Turk J Pediatr
Year:
2021
Document Type:
Article
Affiliation country:
Turkjped.2021.06.021
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