Takotsubo syndrome secondary to vaccination for SARS-CoV-2 Lorenzo Torselletti, Stronati Giulia, Francesca Corraducci, Sara Belleggia
European Heart Journal, Supplement
; 23(SUPPL G):G98-G99, 2021.
Article
in English
| EMBASE | ID: covidwho-1623502
ABSTRACT
Methods and results:
A 79-year-old woman, with a history of subclinical hypothyroidism, obesity and smoke presented to the Emergency Room with dyspnoea and cold sweating. She had undergone her first dose of COVID-19 Moderna mRna vaccination just four days prior to her admission. She showed elevated HS troponin and elevated BNP at her laboratory exams. Her 12-lead ECG showed T wave inversion in the antero-lateral leads and prolongued QTc. Her transthoracic echocardiogram showed severe ejection fraction reduction due to hypokinesia of the mid-apical segments of the anterior and lateral walls of the heart. The patient was then admitted to the Cardiology ward in order to perform a coronary angiography which sowed no significant coronary stenosis. She was started on appropriate medication and discharged after a six day in-hospital stay. At discharge she showed partial recovery of her ejection fraction (EF 44%). A cardiac magnetic resonance was performed after discharge which showed no late gadolinium enhancement. Such finding allowed us to rule out the diagnosis of myocarditis. Moreover at her 3-month follow-up her ejection fraction had recovered completely. We concluded for the diagnosis of Takotsubo Syndrome secondary to vaccination.Conclusions:
We presented a case of Takotsubo syndrome after vaccination with the Moderna vaccine for COVID-19. Two other similar case reports can be found in current medical literature. Female sex, post-menopausal age and the inevitable psychological stress derived by the pandemic and the vaccination may have triggered the condition.
elasomeran; endogenous, compound; gadolinium; troponin; adverse, drug, reaction; aged; cardiology; cardiovascular, magnetic, resonance; case, report; clinical, article; cold, sweat; conference, abstract; coronary, angiography; coronary, artery, obstruction; dyspnea; emergency, ward; female; follow, up; heart, ejection, fraction; hospitalization; human; hypokinesia; male; medical, literature; menopause; mental, stress; myocarditis; nonhuman; obesity; pandemic; QTc, interval; Severe, acute, respiratory, syndrome, coronavirus, 2; side, effect; smoke; subclinical, hypothyroidism; T, wave, inversion; takotsubo, cardiomyopathy; transthoracic, echocardiography; vaccination
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Vaccines
Language:
English
Journal:
European Heart Journal, Supplement
Year:
2021
Document Type:
Article
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