COVID-19: Mutated Strain, Treatment Options and Vaccine Development

ABSTRACT

The ongoing outbreak of the cOviD-19 is a significant threat to global health and the economy. This disease is a highly contagious pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (sARs-cov-2). The virus has a high reproduction rate, due to that it is highly transmittable and has turned into a catastrophe. scientists and researchers worldwide are exaggerating every possible approach to limit the spread of this malicious disease. An abrupt rise has been reported in the number of cases due to newly mutated strains like sARs-cov-2 vUi 2020/12/01. to date, no specific drug is effective in the complete eradication of this dangerous disease but, some broad-spectrum antivirals such as Remdesivir and lopinavir are being used in the management of this ailment. Also, every possible effort has been made in the development of vaccines for preventing the outbreak of this deadly virus. The BNt162b2 by Pfizer and m-RNA-1273 by Moderna have been recently launched into the market, which have shown undesirable effects in geriatrics leading to mortality. in this review, we have tried to highlight important aspects of the cOviD-19 that will aid in global awareness and will help the researchers to investigate possible ways to eradicate this menace and design new moieties for its effectual management. © 2021 Society of Pharmaceutical Sciences of Ankara (FABAD). All rights reserved.