The PRONTO study: Clinical performance of ID NOW in individuals with compatible SARS-CoV-2 symptoms in walk-in centres-accelerated turnaround time for contact tracing.
Can Commun Dis Rep
; 47(12): 534-542, 2021 Dec 09.
Article
in English
| MEDLINE | ID: covidwho-1632788
ABSTRACT
BACKGROUND:
This PRONTO study investigated the clinical performance of the Abbott ID NOWTM (IDN) COVID-19 diagnostic assay used at point of care and its impact on turnaround time for divulgation of test results.METHODS:
Prospective study conducted from December 2020 to February 2021 in acute symptomatic participants presenting in three walk-in centres in the province of Québec.RESULTS:
Valid paired samples were obtained from 2,372 participants. A positive result on either the IDN or the standard-of-care nucleic acid amplification test (SOC-NAAT) was obtained in 423 participants (prevalence of 17.8%). Overall sensitivity of IDN and SOC-NAAT were 96.4% (95% CI 94.2-98.0%) and 99.1% (95% CI 97.6-99.8), respectively; negative predictive values were 99.2% (95% CI 98.7-99.6%) and 99.8% (95% CI 99.5-100%), respectively. Turnaround time for positive results was significantly faster on IDN.CONCLUSION:
In our experience, IDN use in symptomatic individuals in walk-in centres is a reliable sensitive alternative to SOC-NAAT without the need for subsequent confirmation of negative results. Such deployment can accelerate contact tracing, reduce the burden on laboratories and increase access to testing.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
Language:
English
Journal:
Can Commun Dis Rep
Journal subject:
Communicable Diseases
/
Epidemiology
Year:
2021
Document Type:
Article
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