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Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019.
Mertz, Cameron; Glowinski, Rebecca; Cohen, Shira H; Mertz, Sara; Ye, Fang; Hall, Mark W; Peeples, Mark E; King, Tiffany; Wang, Huanyu; Leber, Amy L; Sanchez, Pablo J; Ramilo, Octavio; Mejias, Asuncion.
  • Mertz C; Center for Vaccines and Immunity, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Glowinski R; Center for Vaccines and Immunity, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Cohen SH; Center for Vaccines and Immunity, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Mertz S; Center for Vaccines and Immunity, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Ye F; Center for Vaccines and Immunity, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Hall MW; Department of Pediatrics, Division of Critical Care Medicine, Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Peeples ME; Center for Vaccines and Immunity, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • King T; Center for Vaccines and Immunity, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Wang H; Department of Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Leber AL; Department of Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Sanchez PJ; Center for Perinatal Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Ramilo O; Department of Pediatrics, Division of Neonatology, Nationwide Children\'s Hospital and The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Mejias A; Division of Infectious Diseases, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, Ohio, USA.
J Infect Dis ; 225(2): 208-213, 2022 01 18.
Article in English | MEDLINE | ID: covidwho-1635423
ABSTRACT
The burden of coronavirus disease 2019 (COVID-19) in children represents a fraction of cases worldwide, yet a subset of those infected are at risk for severe disease. We measured plasma severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in a cohort of 103 children hospitalized with COVID-19 with diverse clinical manifestations. SARS-CoV-2 RNAemia was detected in 27 (26%) of these children, lasted for a median of 6 (interquartile range, 2-9) days, and was associated with higher rates of oxygen administration, admission to the intensive care unit, and longer hospitalization.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Nucleic Acid Testing / SARS-CoV-2 / COVID-19 Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Language: English Journal: J Infect Dis Year: 2022 Document Type: Article Affiliation country: Infdis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Nucleic Acid Testing / SARS-CoV-2 / COVID-19 Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Language: English Journal: J Infect Dis Year: 2022 Document Type: Article Affiliation country: Infdis