Characteristics of patients referred to a cardiovascular disease clinic for post-acute sequelae of sars-cov-2 infection
Circulation
; 144(SUPPL 1), 2021.
Article
in English
| EMBASE | ID: covidwho-1638951
ABSTRACT
Introduction:
There is limited literature on the cardiovascular manifestations of post-acute sequelae of SARS-CoV-2 infection (PASC).Methods:
All consecutive adult patients presenting to the cardiology clinic at Yale-New Haven Hospital since July 2020, with positive COVID-19 serologic testing, were included.Results:
Of 71 patients, average age was 46 years (range 19-74 years), 44 (62%) were female. 51 (72%) were White. 19 (27%) patients were hospitalized for COVID-19 (Table). Comorbidities included Hypertension (27%), hyperlipidemia (25%), diabetes (24%), and obesity (30%). On average, patients presented four months after COVID-19 diagnosis. The most common symptoms at presentation were dyspnea (45%, almost all exertional), palpitations (49%), and chest pain/pressure (49%). Patients also had memory impairment (20%), fatigue (39%), and headache (14%). There was no significant difference in cardiopulmonary symptoms (dyspnea, palpitations, and chest pain/pressure) by hospitalization status (p=0.70). TTE was abnormal in 13 of 62 patients and cardiac MRI was abnormal in 10 of 17 patients. Women experienced more cardiopulmonary symptoms (p=0.02) than men. Hospitalized patients were more likely to have ventricular dysfunction than non-hospitalized patients, although there were no significant differences in abnormal MRI findings (p=0.38). Diagnostic yield included nonischemic cardiomyopathy (6%);new ischemia (3%);coronary vasospasm (1%);new atrial fibrillation (1%);possible myocarditis based on symptoms, MRI LGE (8%) or inflammation (3%). Two people met POTS criteria;majority of patients had evidence of sinus tachycardia and exertional fatigue consistent with orthostatic intolerance and deconditioning.Conclusions:
In this cohort of patients referred to a cardiology clinic for PASC, cardiopulmonary symptoms did not differ by hospitalization status, however women were more likely to experience these symptoms than men.
unclassified, drug; adult; aged; atrial, fibrillation; cardiology; cardiovascular, magnetic, resonance; cohort, analysis; comorbidity; complication; conference, abstract; controlled, study; coronary, artery, spasm; COVID-19, serological, testing; deconditioning; diabetes, mellitus; diagnostic, value; dyspnea; fatigue; female; headache; heart, palpitation; heart, ventricle, function; hospital, patient; hospitalization; human; hyperlipidemia; hypertension; ischemia; major, clinical, study; male; memory, disorder; middle, aged; myocarditis; nonischemic, cardiomyopathy; obesity; orthostatic, intolerance; sinus, tachycardia; thorax, pain
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Long Covid
Language:
English
Journal:
Circulation
Year:
2021
Document Type:
Article
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