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Ocular transmissibility of COVID-19: possibilities and perspectives.
Davis, Gavin; Li, Kin; Thankam, Finosh G; Wilson, Daniel R; Agrawal, Devendra K.
  • Davis G; Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second Street, Pomona, CA, 91766, USA.
  • Li K; Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second Street, Pomona, CA, 91766, USA.
  • Thankam FG; Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second Street, Pomona, CA, 91766, USA.
  • Wilson DR; Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second Street, Pomona, CA, 91766, USA.
  • Agrawal DK; Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second Street, Pomona, CA, 91766, USA. DAgrawal@WesternU.edu.
Mol Cell Biochem ; 477(3): 849-864, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-1640941
ABSTRACT
Since the initial outbreak of coronavirus disease 2019 (COVID-19), extensive research has emerged from across the globe to understand the pathophysiology of this novel coronavirus. Transmission of this virus is a subject of particular interest as researchers work to understand which protective and preventative measures are most effective. Despite the well understood model of aerosol-respiratory mediated transmission, the exact mechanism underlying the inoculation, infection and spread of COVID-19 is currently unknown. Given anatomical positioning and near constant exposure to aerosolized pathogens, the eye may be a possible gateway for COVID-19 infection. This critical review explores the possibility of an ocular-systemic or ocular-nasal-pulmonic pathway of COVID-19 infection and includes novel insights into the possible immunological mechanisms leading to cytokine surge.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Eye Infections, Viral / COVID-19 Type of study: Reviews Limits: Humans Language: English Journal: Mol Cell Biochem Year: 2022 Document Type: Article Affiliation country: S11010-021-04336-6

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Eye Infections, Viral / COVID-19 Type of study: Reviews Limits: Humans Language: English Journal: Mol Cell Biochem Year: 2022 Document Type: Article Affiliation country: S11010-021-04336-6