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Efficacy of COVID-19 vaccine booster doses in older people.
Mattiuzzi, Camilla; Lippi, Giuseppe.
  • Mattiuzzi C; Service of Clinical Governance, Provincial Agency for Social and Sanitary Services, Trento, Italy.
  • Lippi G; Section of Clinical Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, School of Medicine, University of Verona, P.le L.A Scuro, 10, 37134, Verona, Italy. giuseppe.lippi@univr.it.
Eur Geriatr Med ; 13(1): 275-278, 2022 02.
Article in English | MEDLINE | ID: covidwho-1649141
ABSTRACT

PURPOSE:

We provide here an updated analysis on efficacy of COVID-19 vaccine booster doses in older people (i.e., aged ≥ 80 years) based on ongoing Italian nationwide COVID-19 vaccination campaign.

METHODS:

Data were obtained from the COVID-19 national integrated surveillance program, made available and regularly updated by the Italian National Institute of Health.

RESULTS:

Compared to those who completed the COVID-19 vaccination cycle for ≥ 5 months (n = 2,385,897), those receiving booster doses (n = 1,549,747) had 75% lower risk of SARS-CoV-2 infection, 82-83% lower risk of COVID-19 hospitalization and ICU admission, and 81% lower risk of death. Administration of COVID-19 vaccine boosters generated also greater protection (between 63 and 87% higher) against all these same endpoints compared to early completing (i.e., < 5 months; n = 335,458) a primary COVID-19 vaccination cycle.

CONCLUSIONS:

The administration of COVID-19 vaccine booster doses is advisable for reducing the risk of morbidity and mortality in older people.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Topics: Vaccines Limits: Aged / Humans Language: English Journal: Eur Geriatr Med Year: 2022 Document Type: Article Affiliation country: S41999-022-00615-7

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Topics: Vaccines Limits: Aged / Humans Language: English Journal: Eur Geriatr Med Year: 2022 Document Type: Article Affiliation country: S41999-022-00615-7