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High SARS-CoV-2 Prevalence among Healthcare Workers in Cochabamba, Bolivia.
Saba Villarroel, Paola Mariela; Castro Soto, María Del Rosario; Undurraga, Verónica; Sanz, Heydi; Jaldín, Ana María; Ninove, Laetitia; Nurtop, Elif; Pezzi, Laura; Mohamed Ali, Souand; Amroun, Abdennour; Seston, Morgan; de Lamballerie, Xavier.
  • Saba Villarroel PM; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
  • Castro Soto MDR; Infectology Department, Viedma Hospital, Cochabamba 4780, Bolivia.
  • Undurraga V; María de los Ángeles Clinic, Cochabamba 4780, Bolivia.
  • Sanz H; Manuel Ascencio Villarroel Hospital, Cochabamba 4780, Bolivia.
  • Jaldín AM; Clínica Copacabana, Cochabamba 4780, Bolivia.
  • Ninove L; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
  • Nurtop E; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
  • Pezzi L; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
  • Mohamed Ali S; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
  • Amroun A; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
  • Seston M; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
  • de Lamballerie X; Aix-Marseille Univ, IRD 190, Inserm 1207, Unité des Virus Émergents (UVE), 27 Boulevard Jean Moulin, 13005 Marseille, France.
Viruses ; 14(2)2022 01 25.
Article in English | MEDLINE | ID: covidwho-1649410
ABSTRACT
Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. The aim of the study was to estimate the SARS-CoV-2 seroprevalence among HCWs in Cochabamba, Bolivia and to determine the potential risk factors. In January 2021, a cross-sectional SARS-CoV-2 seroprevalence study was conducted in 783 volunteer clinical and non-clinical HCWs in tertiary care facilities. It was based on IgG detection using ELISA, chemiluminiscence, and seroneutralisation tests from dried blood spots. Analysis revealed a high seroprevalence (43.4%) of SARS-CoV-2 IgG antibodies. The combination of anosmia and ageusia (OR 68.11; 95%-CI 24.83-186.80) was predictive of seropositivity. Belonging to the cleaning staff (OR 1.94; 95%-CI 1.09-3.45), having more than two children in the same house (OR 1.74; 95%-CI 1.12-2.71), and having been in contact with a close relative with COVID-19 (OR 3.53; 95%-CI 2.24-5.58) were identified as risk factors for seropositivity in a multivariate analysis. A total of 47.5% of participants had received medication for COVID-19 treatment or prevention, and only ~50% of symptomatic subjects accessed PCR or antigenic testing. This study confirms a massive SARS-CoV-2 attack rate among HCWs in Cochabamba by the end of January 2021. The main risk factors identified are having a low-skilled job, living with children, and having been in contact with an infected relative in the household.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Health Personnel / COVID-19 / Antibodies, Viral Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: South America / Bolivia Language: English Year: 2022 Document Type: Article Affiliation country: V14020232

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Health Personnel / COVID-19 / Antibodies, Viral Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: South America / Bolivia Language: English Year: 2022 Document Type: Article Affiliation country: V14020232