[Leukocytoclastic vasculitis and acute renal failure following inactivated SARS-CoV-2 vaccine]. / Vascularite leucocytoclasique et néphrite interstitielle aiguë après vaccin à SARS-CoV-2 inactivé.
Nephrol Ther
; 18(4): 287-290, 2022 Jul.
Article
in French
| MEDLINE | ID: covidwho-1649775
ABSTRACT
SARS-CoV-2 vaccines are being administered worldwide. Most side effects are mild and self-limiting with few reported cases of severe reactions. We report a case of leukocytoclastic vasculitis with acute kidney failure following aninactivated SARS-CoV-2 vaccine, unique for its dramatic visual presentation and its rapid response to treatment. This is the case of a 58years-old man presenting with fever, arthralgias and vascular purpura on his limbs associated with acute kidney failure requiring hemodialysis nine days after anti-COVID-19 vaccination. Skin biopsy revealed a leukocytoclastic vasculitis and a renal biopsy showed an acute tubulointerstitial nephritis. The vascular purpura resolved 7days after initiating treatment with prednisone but the patient remains in chronic renal failure. The analysis and investigation of the complications and adverse events induced by anti-COVID-19 vaccines could increase our understanding of the underlying pathogenesis.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Acute Kidney Injury
/
COVID-19 Vaccines
/
COVID-19
Type of study:
Case report
/
Observational study
Topics:
Long Covid
/
Vaccines
Limits:
Humans
/
Male
Language:
French
Journal:
Nephrol Ther
Journal subject:
Nephrology
/
Therapeutics
Year:
2022
Document Type:
Article
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