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Medication adherence in systemic lupus erythematosus during Brazilian COVID-19 pandemic.
Albuquerque, Emmanuele S; Pinto, Larissa dS; Neto, Valfrido LdM; Fragoso, Thiago S.
  • Albuquerque ES; Faculty of Medicine, 469043Federal University of Alagoas, Maceio, Brazil.
  • Pinto LD; Faculty of Medicine, 469043Federal University of Alagoas, Maceio, Brazil.
  • Neto VL; Faculty of Medicine, 469043Federal University of Alagoas, Maceio, Brazil.
  • Fragoso TS; Faculty of Medicine, 469043Federal University of Alagoas, Maceio, Brazil.
Lupus ; 31(2): 221-227, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1649860
ABSTRACT

BACKGROUND:

Patients with chronic diseases are potential candidates for inadequate follow-up of drug therapy, tending to incur damage to the intended results. This deserves greater attention in the pandemic period, as they are in the considered risk group.

METHODS:

We aim to assess Treatment Adherence Measure and analyze associations with characteristics related to the patient, treatment, disease, health professionals and service, and sociodemographic issues in patients with Systemic Lupus Erythematosus (SLE). W conducted a cross-sectional study with a sample of 116 participants, whose data were collected through individual interviews and review of medical records, during the first months of the COVID-19 pandemic in Brazil. Adherence was measured using the Treatment Adherence Measure, and associations were evidenced through described and inferential statistics.

RESULTS:

The percentage of adherent patients was 55.2%. An association was found between MTA (Medication Treatment Adherence) and physical exercise practice (p = 0.032), and difficulties with treatment (p = 0.002).

Conclusion:

Participants who did not practice physical exercise were 3.71 times more likely to not adhere to the treatment. Individuals who identified difficulties in the treatment were 3.43 times more likely to not adhere to the treatment; we believe that the pandemic may have influenced this result. More targeted studies are needed to measure the impact on MTA in these patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Medication Adherence / COVID-19 / Lupus Erythematosus, Systemic Type of study: Cohort study / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Country/Region as subject: South America / Brazil Language: English Journal: Lupus Journal subject: Rheumatology Year: 2022 Document Type: Article Affiliation country: 09612033221074177

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Medication Adherence / COVID-19 / Lupus Erythematosus, Systemic Type of study: Cohort study / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Country/Region as subject: South America / Brazil Language: English Journal: Lupus Journal subject: Rheumatology Year: 2022 Document Type: Article Affiliation country: 09612033221074177