POSA383 Identification of Risk Factors Associated with COVID-19 Hospitalization
Value in Health
; 25(1):S248, 2022.
Article
in English
| EMBASE | ID: covidwho-1650250
ABSTRACT
Objectives:
A detailed understanding around the risk factors associated with COVID-19 infection will help in understanding the disease prognosis, resource utilization, and treatment. This study evaluated the risk factors associated with hospitalization in patients with COVID-19 infection.Methods:
This retrospective observational study included patients diagnosed with COVID-19 infection between 1st April to 30th September 2020 with ICD-10 CM diagnosis recorded in a large deidentified database of US health insurance claims. Patients having continuous enrollment between 1 year before (baseline period) to 3 months post (follow-up period) first diagnosis of COVID-19 (index date) were included in study. Comorbid conditions were identified using ICD-10 CM codes during the 1-year baseline period. The primary outcome variable was the hospitalizations due to COVID-19. Multivariate regression model was used to assess the association between sociodemographic characteristics, baseline comorbid conditions and hospitalization related to COVID-19.Results:
The study included 176,284 patients with diverse race/ethnicity (83,863 [47.6%] White, 18,708 [10.6%] African-American, and 27,211 [15.4%] Hispanic), a mean (SD) age of 55.5 (21.9) years and 44% males. Regression adjusted clinical predictors for hospitalization included asthma (OR 1.27 CI 1.21-1.32), chronic kidney disease (OR 1.38 CI 1.34-1.43), chronic obstructive pulmonary disease (OR 1.20 CI 1.16-1.25), diabetes (OR 1.30 CI 1.26-1.34), hyperlipidemia (OR 1.12 CI 1.09-1.16), hypertension (OR 1.54 CI 1.49-1.60), ischemic heart disease (OR 1.15 CI 1.11-1.19), rheumatoid arthritis / osteo arthritis (OR 1.09 CI 1.06-1.13), prostate cancer (OR 1.11 CI 1.03-1.20), endometrial cancer (OR 1.29 CI 1.05-1.57) and lung cancer (OR 1.35 CI 1.18-1.54). Demographics related risk factors included male sex (OR 1.29 CI 1.25-1.33) older age->=55 years (OR 1.77 CI 1.70-1.85) and African-American race (OR 1.58 CI 1.51-1.65) and Hispanic race (OR 1.25 CI 1.20-1.30).Conclusions:
In this study COVID-19 hospitalizations were significantly associated with older age, male sex, and comorbidity burden. Prospective studies are needed to understand mechanism and causality.
adult; African, American; age; aged; asthma; cancer, patient; chronic, kidney, failure; chronic, obstructive, lung, disease; comorbidity; conference, abstract; controlled, study; coronavirus, disease, 2019; demography; endometrium, cancer; ethnicity; female; follow, up; health, insurance; Hispanic; human; hyperlipidemia; hypertension; ICD-10-CM; insulin, dependent, diabetes, mellitus; ischemic, heart, disease; lung, cancer; major, clinical, study; male; middle, aged; observational, study; outcome, assessment; outcome, variable; prospective, study; prostate, cancer; race; retrospective, study; rheumatoid, arthritis; risk, assessment; risk, factor
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Prognostic study
Language:
English
Journal:
Value in Health
Year:
2022
Document Type:
Article
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