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POSA384 Identification of Complications Associated with COVID-19 Infection from Claims Data
Value in Health ; 25(1):S248, 2022.
Article in English | EMBASE | ID: covidwho-1650251
ABSTRACT

Objectives:

Growing evidences suggest that COVID-19 infection should be considered as a systemic disease which involves multiple organ systems leading to numerous respiratory and non-respiratory complications. The current study evaluated all the potential complications associated with COVID-19 infections from administrative claims data.

Methods:

This retrospective, cross-over and observational study included patients diagnosed with COVID-19 infection between 1st April to 30th September 2020 with ICD-10 CM diagnosis recorded in the a large deidentified database of US health insurance claims. Only the patients having continuous eligibility between 4 months before (baseline period) to 1-month post (follow-up period) the first diagnosis of COVID-19 (index date) were included in study. Frequency of all ICD-10-CM diagnosis codes occurring during baseline period and during follow-up period were evaluated. For every ICD-10 CM diagnosis code, the risk estimates and odds ratios (ORs) of association with COVID-19 were evaluated.

Results:

The study included 208,886 patients with a mean (SD) age of 53.65 (21.4) years, 44% males and 56% females. 486 out of 1,564 ICD codes evaluated found to be statistically significant with COVID-19 infection exposure. Notable disorders having higher odds and high absolute risk included viral pneumonia (OR 90.09;CI73.12-111.00;absolute risk 16.12%), acute respiratory distress syndrome (OR 46.92;CI28.42-77.48;absolute risk 1.5%), respiratory failure (OR 17.44;CI16.18-18.81;absolute risk 10.74%), sepsis (OR 7.94;CI7.21-8.75;absolute risk 5.25%), acute kidney failure (OR 5.70;CI5.33-6.09;absolute risk 6.30%), essential hypertension (OR 1.78;CI1.74-1.82;absolute risk 16.77%), Ischemic heart disease (OR 1.97;CI1.88-2.05;absolute risk 4.46%) and heart failure (OR 2.39;CI2.27-2.51;absolute risk 3.58%).

Conclusions:

Apart from respiratory system which is the primary site of infection for COVID-19, many other organs like cardiovascular, kidney and liver with varying degree are also involved in COVID-19 infection.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Value in Health Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Value in Health Year: 2022 Document Type: Article