POSA384 Identification of Complications Associated with COVID-19 Infection from Claims Data
Value in Health
; 25(1):S248, 2022.
Article
in English
| EMBASE | ID: covidwho-1650251
ABSTRACT
Objectives:
Growing evidences suggest that COVID-19 infection should be considered as a systemic disease which involves multiple organ systems leading to numerous respiratory and non-respiratory complications. The current study evaluated all the potential complications associated with COVID-19 infections from administrative claims data.Methods:
This retrospective, cross-over and observational study included patients diagnosed with COVID-19 infection between 1st April to 30th September 2020 with ICD-10 CM diagnosis recorded in the a large deidentified database of US health insurance claims. Only the patients having continuous eligibility between 4 months before (baseline period) to 1-month post (follow-up period) the first diagnosis of COVID-19 (index date) were included in study. Frequency of all ICD-10-CM diagnosis codes occurring during baseline period and during follow-up period were evaluated. For every ICD-10 CM diagnosis code, the risk estimates and odds ratios (ORs) of association with COVID-19 were evaluated.Results:
The study included 208,886 patients with a mean (SD) age of 53.65 (21.4) years, 44% males and 56% females. 486 out of 1,564 ICD codes evaluated found to be statistically significant with COVID-19 infection exposure. Notable disorders having higher odds and high absolute risk included viral pneumonia (OR 90.09;CI73.12-111.00;absolute risk 16.12%), acute respiratory distress syndrome (OR 46.92;CI28.42-77.48;absolute risk 1.5%), respiratory failure (OR 17.44;CI16.18-18.81;absolute risk 10.74%), sepsis (OR 7.94;CI7.21-8.75;absolute risk 5.25%), acute kidney failure (OR 5.70;CI5.33-6.09;absolute risk 6.30%), essential hypertension (OR 1.78;CI1.74-1.82;absolute risk 16.77%), Ischemic heart disease (OR 1.97;CI1.88-2.05;absolute risk 4.46%) and heart failure (OR 2.39;CI2.27-2.51;absolute risk 3.58%).Conclusions:
Apart from respiratory system which is the primary site of infection for COVID-19, many other organs like cardiovascular, kidney and liver with varying degree are also involved in COVID-19 infection.
acute, kidney, failure; adult; adult, respiratory, distress, syndrome; complication; conference, abstract; controlled, study; coronavirus, disease, 2019; diagnosis; eligibility; essential, hypertension; female; follow, up; health, insurance; heart, failure; human; ICD-10-CM; ischemic, heart, disease; liver; major, clinical, study; male; middle, aged; observational, study; respiratory, failure; retrospective, study; risk, assessment; sepsis; virus, pneumonia
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Value in Health
Year:
2022
Document Type:
Article
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