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Successful use of veno-venous extracorporeal membrane oxygenation for acute chest syndrome in a child with sickle cell disease and SARS-CoV-2.
Koh, Wonshill; Malik, Punam; Whitehead, Jason; Morales, David Luis Simon; Hayes, Don.
  • Koh W; Cincinnati Children's Hospital Medical Center, The Heart Institute, Cincinnati, Ohio, USA.
  • Malik P; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Whitehead J; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Morales DLS; Comprehensive Sickle Cell Center, Cincinnati Children's Hospital Medical Center, Division of Cancer and Blood Diseases, Cincinnati, Ohio, USA.
  • Hayes D; The ECMO Program, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Pediatr Pulmonol ; 57(4): 1096-1099, 2022 04.
Article in English | MEDLINE | ID: covidwho-1650861
ABSTRACT
Children with sickle cell disease (SCD) are at increased risk for severe illness due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe the successful native lung recovery of a child with SCD referred for lung transplant (LTx) evaluation who was on prolonged veno-venous extracorporeal membrane oxygenation (VV-ECMO). He initially presented with acute chest syndrome complicated by SARS-CoV-2 infection that ultimately required dual-lumen, single bicaval VV-ECMO cannulation for respiratory support. Despite the increased risk of hemolysis and thrombosis from SCD and SARS-CoV-2 infection, he was successfully supported on VV-ECMO for 71 days without complications leading to native lung recovery with meticulous management of his SCD therapy. This report provides new insight on our approach to VV-ECMO support in a child with SCD and SARS-CoV-2 infection. With a successful outcome, the patient has returned home but still on mechanical ventilation with LTx still an option if he is not eventually liberated from invasive respiratory support.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation / Acute Chest Syndrome / COVID-19 / Anemia, Sickle Cell Type of study: Experimental Studies / Prognostic study Topics: Long Covid Limits: Child / Humans / Male Language: English Journal: Pediatr Pulmonol Journal subject: Pediatrics Year: 2022 Document Type: Article Affiliation country: Ppul.25843

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Extracorporeal Membrane Oxygenation / Acute Chest Syndrome / COVID-19 / Anemia, Sickle Cell Type of study: Experimental Studies / Prognostic study Topics: Long Covid Limits: Child / Humans / Male Language: English Journal: Pediatr Pulmonol Journal subject: Pediatrics Year: 2022 Document Type: Article Affiliation country: Ppul.25843