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Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective.
Prasher, Parteek; Sharma, Mousmee; Mehta, Meenu; Paudel, Keshav R; Satija, Saurabh; Chellappan, Dinesh K; Dureja, Harish; Gupta, Gaurav; Tambuwala, Murtaza M; Negi, Poonam; Wich, Peter R; Hansbro, Nicole G; Hansbro, Philip M; Dua, Kamal.
  • Prasher P; Department of Chemistry, University of Petroleum & Energy Studies, Dehradun, 248007, India.
  • Sharma M; Department of Chemistry, Uttaranchal University, Dehradun, 248007, India.
  • Mehta M; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia.
  • Paudel KR; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia; School of Life Sciences, Faculty of Science, University of Technology Sydney, Ultimo, NSW, 2007, Australia.
  • Satija S; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144411, Punjab, India.
  • Chellappan DK; Department of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.
  • Dureja H; Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
  • Gupta G; School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur, India.
  • Tambuwala MM; School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine, County Londonderry, BT52 1SA, Northern Ireland, United Kingdom.
  • Negi P; School of Pharmaceutical Sciences, Shoolini University, Bajhol, Sultanpur, Solan, Himachal Pradesh, 173229, India.
  • Wich PR; Australian Centre for NanoMedicine, University of New South Wales, Sydney, NSW, 2052, Australia; School of Chemical Engineering, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Hansbro NG; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia; School of Life Sciences, Faculty of Science, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Scie
  • Hansbro PM; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia; School of Life Sciences, Faculty of Science, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Scie
  • Dua K; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia; School of Pharmaceutical Sciences, Shoolini University, Bajhol, Sultanpur, Solan, Himachal Pradesh, 173229, In
Chem Biol Interact ; 325: 109125, 2020 Jul 01.
Article in English | MEDLINE | ID: covidwho-165367
ABSTRACT
The apparent predicament of the representative chemotherapy for managing respiratory distress calls for an obligatory deliberation for identifying the pharmaceuticals that effectively counter the contemporary intricacies associated with target disease. Multiple, complex regulatory pathways manifest chronic pulmonary disorders, which require chemotherapeutics that produce composite inhibitory effect. The cost effective natural product based molecules hold a high fervor to meet the prospects posed by current respiratory-distress therapy by sparing the tedious drug design and development archetypes, present a robust standing for the possible replacement of the fading practice of poly-pharmacology, and ensure the subversion of a potential disease relapse. This study summarizes the experimental evidences on natural products moieties and their components that illustrates therapeutic efficacy on respiratory disorders.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Tract Diseases / Plant Extracts / Molecular Targeted Therapy Limits: Animals / Humans Language: English Journal: Chem Biol Interact Year: 2020 Document Type: Article Affiliation country: J.cbi.2020.109125

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Tract Diseases / Plant Extracts / Molecular Targeted Therapy Limits: Animals / Humans Language: English Journal: Chem Biol Interact Year: 2020 Document Type: Article Affiliation country: J.cbi.2020.109125