Bioinformatics approaches to natural product discovery
BIO Web of Conferences
; 41(4), 2021.
Article
in English
| CAB Abstracts | ID: covidwho-1655690
ABSTRACT
Introduction:
Bioinformatics is a multi-disciplinary field that usually uses approaches in Computer Science such as algorithms and machine learning to solve problems in the domains of Biology, Biochemistry, and other domains involving molecular biology data. This approach can also be used to screen natural products that have certain properties. Jamu or Indonesian herbal medicine works with the principle of multi-component multi-target. This principle focuses on the complex interactions of system components that describe how multi-components (compounds) can work together to affect multi-targets (protein targets). This mechanism is also popularly called Network Pharmacology. In this study, we introduce a workflow to screen herbal compounds based on Network Pharmacology and machine learning approach.
Information, and, Documentation, [CC300]; Prion, Viral, Bacterial, and, Fungal, Pathogens, of, Humans, [VV210]; Molecular, Biology, and, Molecular, Genetics, [ZZ360]; Nutrition, related, Disorders, and, Therapeutic, Nutrition, [VV130]; Pharmacology, [VV730]; Pesticides, and, Drugs; Control, [HH405]; Non-food/Non-feed, Plant, Products, [SS200]; Animal, and, in, vitro, Models, for, Pharmaceuticals, [VV450]; bioinformatics; natural, products; herbal, drugs; pharmacology; proteins; obesity; coronavirus, disease, 2019; antiinflammatory, properties; medicinal, plants; machine, learning; computer, techniques; inflammation; viral, diseases; human, diseases; plant, extracts; adipose, tissue; in, vitro; clinical, trials; Andrographis, paniculata; Murraya, paniculata; Severe, acute, respiratory, syndrome, coronavirus, 2; man; plants; Andrographis; Acanthaceae; Lamiales; eudicots; angiosperms; Spermatophyta; eukaryotes; Murraya; Rutaceae; Sapindales; Severe, acute, respiratory, syndrome-related, coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense, ssRNA, Viruses; ssRNA, Viruses; RNA, Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; herbal, medicines; fatness; anti-inflammatory, properties; drug, plants; medicinal, herbs; officinal, plants; computer, applications; SARS-CoV-2; viral, infections
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
BIO Web of Conferences
Year:
2021
Document Type:
Article
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