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Antiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19
Mehta, Ravi, Chekmeneva, Elena, Jackson, Heather, Sands, Caroline, Mills, Ewurabena, Arancon, Dominique, Li, Ho Kwong, Arkell, Paul, Rawson, Timothy M.; Hammond, Robert, Amran, Maisarah, Haber, Anna, Cooke, Graham, Noursadeghi, Mahdad, Kaforou, Myrsini, Lewis, Matthew R.; Takats, Zoltan, Sriskandan, Shiranee.
Med (New York, N.Y.) ; 2022.
Article in English | EuropePMC | ID: covidwho-1661289
ABSTRACT
Mehta et al. perform untargeted metabolic profiling of serum samples from patients presenting to the emergency department with different infections. The antiviral small molecule 3’-Deoxy-3’,4’-didehydro-cytidine (ddhC) was detectable in human serum and accurately differentiated viral infections from other infection syndromes in both a discovery and validation patient cohort.
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Collection: Databases of international organizations Database: EuropePMC Language: English Journal: Med (New York, N.Y.) Year: 2022 Document Type: Article

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Collection: Databases of international organizations Database: EuropePMC Language: English Journal: Med (New York, N.Y.) Year: 2022 Document Type: Article