Myalgia and fatigue as long term symptoms in COVID-19 patients: A 1-year follow-up
Acta Myologica
; 40(SUPPL 1):32, 2021.
Article
in English
| EMBASE | ID: covidwho-1663114
ABSTRACT
Background. COVID-19 is caused by SARS-CoV-2 virus and in many cases lead to a pneumonia. However a number of neumuscular manifestations have been associated to SARS-CoV-2 infection. Furthermore, multiorgan symptoms after COVID-19 are being reported by increasing numbers of patients, ranging from cough to fatigue and muscle pain. However, the long-term health consequences of COVID-19 remain largely unclear. Methods:
We evaluated 124 patients hospitalized between march and May 2020 for SARS-COV-2 associated pneumonia at 6 and 12 months. We retrospectively collected clinical, laboratory and radiological information available. for each patient, cognitive tests, scales for depression and anxiety and a specific Fatigue Severity Scale (FSS) were performed. Results. Twenty-five patients died during hospitalization. At 12 months follow up 85 patient were evaluated. Eighty-seven (70%) patiens were male and mean age was 67.3 years. During hospitalization 43 (36.5%) of patients complain of myalgia. This patients had higher CK levels than patients who did not (534 U/L vs 93 U/l, p < 0.001). At 12 months 42% of patients complain about myalgia while 34% about fatigue. Mean FSS value were 32.93, and were significatively higher in patiets who complain about fatigue (41.52 vs 27.08 p < 0.001) and Muscle pain (40.84 vs 26.80, p < 0.001) compared to who did not. Conclusions. During hospitalization for COVID-19 myalgia was associated with an higher level of CK, suggesting a possible muscle involvement. At 12 month myalgia and fatigue were present in a more than a third of patient suggesting that this manifestation could be one of the main COVID-19 sequelae.
aged; anxiety; clinical evaluation; clinical laboratory; complication; conference abstract; controlled study; coronavirus disease 2019; coughing; depression; fatigue; Fatigue Severity Scale; female; follow up; hospital mortality; hospitalization; human; major clinical study; male; myalgia; nonhuman; pneumonia; retrospective study; Severe acute respiratory syndrome coronavirus 2
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Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Cohort study
/
Prognostic study
Topics:
Long Covid
Language:
English
Journal:
Acta Myologica
Year:
2021
Document Type:
Article
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