Ambient Temperature Stable, Scalable COVID-19 Polymer Particle Vaccines Induce Protective Immunity (Adv. Healthcare Mater. 3/2022)

ABSTRACT

Sars-CoV-2 Vaccines In article number 2102089 by Bernd H. A. Rehm and co-workers, an ambient temperature-stable, scalable COVID-19 polymer particle vaccines are developed by engineering endotoxinfree bacterial cell factories to self-assemble biopolymer particles coated with immunogenic SARS-CoV-2 antigens. Polymer particle vaccines induce protective immunity in a hamster SARS-CoV-2 infection model reducing virus titers up to viral clearance in lungs post infection.