Your browser doesn't support javascript.
Emerging Knowledge of the Neurobiology of COVID-19.
Butler, Matthew; Cross, Benjamin; Hafeez, Danish; Lim, Mao Fong; Morrin, Hamilton; Rengasamy, Emma Rachel; Pollak, Tom; Nicholson, Timothy R.
  • Butler M; Institute of Psychiatry, Psychology and Neuroscience, King's College, 16 De Crespigny Park, SE5 8AF London. Electronic address: Matthew.butler@kcl.ac.uk.
  • Cross B; East Lancashire Hospitals NHS Trust, Casterton Ave, Burnley, BB10 2PQ.
  • Hafeez D; School of Medical Sciences, The University of Manchester, Oxford Rd, Manchester, M13 9PL, UK.
  • Lim MF; Cambridge University Hospitals NHS Foundation Trust, Hills Rd, Cambridge, CB2 0QQ, UK.
  • Morrin H; Maidstone & Tunbridge Wells NHS Trust, Tonbridge Rd, Royal Tunbridge Wells, TN2 4QJ, UK.
  • Rengasamy ER; Cwm Taf Morgannwg University Health Board, Ynysmeurig House, Navigation Park, Abercynon, CF45 4SN, UK.
  • Pollak T; Institute of Psychiatry, Psychology and Neuroscience, King's College, 16 De Crespigny Park, SE5 8AF London.
  • Nicholson TR; Institute of Psychiatry, Psychology and Neuroscience, King's College, 16 De Crespigny Park, SE5 8AF London.
Psychiatr Clin North Am ; 45(1): 29-43, 2022 03.
Article in English | MEDLINE | ID: covidwho-1665392
ABSTRACT
Many patients with COVID-19 will experience acute or longer-term neuropsychiatric complications. The neurobiological mechanisms behind these are beginning to emerge; however, the neurotropic hypothesis is not strongly supported by clinical data. The inflammatory response to SARS-CoV-2 is likely to be responsible for delirium and other common acute neuropsychiatric manifestations. Vascular abnormalities such as endotheliopathies contribute to stroke and cerebral microbleeds, with their attendant neuropsychiatric sequelae. Longer-term neuropsychiatric syndromes fall into 2 broad categories neuropsychiatric deficits occurring after severe (hospitalized) COVID-19 and "long COVID," which occurs in many patients with a milder acute COVID-19 illness.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Nervous System Diseases Type of study: Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Psychiatr Clin North Am Year: 2022 Document Type: Article

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Nervous System Diseases Type of study: Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Psychiatr Clin North Am Year: 2022 Document Type: Article