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Outcomes of critically ill COVID-19 survivors and caregivers: a case study-centred narrative review Devenir des survivants et des soignants gravement atteints par la COVID-19 : une revue narrative centrée sur une étude de cas
Canadian journal of anaesthesia = Journal canadien d'anesthesie ; : 1-14, 2022.
Article in English | EuropePMC | ID: covidwho-1668496
ABSTRACT
Purpose Critical illness is a transformative experience for both patients and their family members. For COVID-19 patients admitted to the intensive care unit (ICU), survival may be the start of a long road to recovery. Our knowledge of the post-ICU long-term sequelae of acute respiratory distress syndrome (ARDS) and severe acute respiratory syndrome (SARS) may inform our understanding and management of the long-term effects of COVID-19. Source We identified international and Canadian epidemiologic data on ICU admissions for COVID-19, COVID-19 pathophysiology, emerging ICU practice patterns, early reports of long-term outcomes, and federal support programs for survivors and their families. Centred around an illustrating case study, we applied relevant literature from ARDS and SARS to contextualize knowledge within emerging COVID-19 research and extrapolate findings to future long-term outcomes. Principal findings COVID-19 is a multisystem disease with unknown long-term morbidity and mortality. Its pathophysiology is distinct and unique from ARDS, SARS, and critical illness. Nevertheless, based on initial reports of critical care management for COVID-19 and the varied injurious supportive practices employed in the ICU, patients and families are at risk for post-intensive care syndrome. The distinct incremental risk of COVID-19 multiple organ dysfunction is unknown. The risk of mood disorders in family members may be further exacerbated by imposed isolation and stigma. Conclusion Emerging literature on COVID-19 outcomes suggests some similarities with those of ARDS/SARS and prolonged mechanical ventilation. The pathophysiology of COVID-19 is presented here in the context of early outcome data and to inform an agenda for longitudinal research for patients and families.
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Collection: Databases of international organizations Database: EuropePMC Type of study: Case report / Prognostic study / Reviews Language: English Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie Year: 2022 Document Type: Article

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Collection: Databases of international organizations Database: EuropePMC Type of study: Case report / Prognostic study / Reviews Language: English Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie Year: 2022 Document Type: Article