Aedes mosquitoes in the emerging threat of urban yellow fever transmission.
Rev Med Virol
; 32(4): e2333, 2022 07.
Article
in English
| MEDLINE | ID: covidwho-1669637
ABSTRACT
This last decade has seen a resurgence of yellow fever (YF) in historical endemic regions and repeated attempts of YF introduction in YF-free countries such as the Asia-Pacific region and the Caribbean. Infected travellers are the main entry routes in these regions where competent mosquito vectors proliferate in appropriate environmental conditions. With the discovery of the 17D vaccine, it was thought that YF would be eradicated. Unfortunately, it was not the case and, contrary to dengue, chikungunya and Zika, factors that cotribute to YF transmission remain under investigation. Today, all the signals are red and it is very likely that YF will be the next pandemic in the YF-free regions where millions of people are immunologically naïve. Unlike COVID-19, YF is associated with a high case-fatality rate and a high number of deaths are expected. This review gives an overview of global YF situation, including the non-endemic Asia-Pacific region and the Caribbean where Aedes aegypti is abundantly distributed, and also proposes different hypotheses on why YF outbreaks have not yet occurred despite high records of travellers importing YF into these regions and what role Aedes mosquitoes play in the emergence of urban YF.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Yellow Fever
/
Aedes
/
Chikungunya Fever
/
Zika Virus
/
Zika Virus Infection
/
COVID-19
Type of study:
Observational study
Topics:
Vaccines
Limits:
Animals
/
Humans
Language:
English
Journal:
Rev Med Virol
Journal subject:
Virology
Year:
2022
Document Type:
Article
Affiliation country:
Rmv.2333
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