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SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)-pilot: A feasibility study.
Chew, Kimberly Ann; Xu, Xin; Siongco, Paula; Villaraza, Steven; Phua, April Ka Sin; Wong, Zi Xuen; Chung, Chooi Yu; Tang, Ning; Chew, Effie; Henry, Christiani Jeyakumar; Koo, Edward; Chen, Christopher.
  • Chew KA; Memory, Ageing and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
  • Xu X; Memory, Ageing and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
  • Siongco P; School of Public Health and the 2nd Affiliated Hospital of School of Medicine Zhejiang University Hangzhou China.
  • Villaraza S; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Phua AKS; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Wong ZX; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Chung CY; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Tang N; Clinical Nutrition Research Centre Singapore Institute for Clinical Sciences Agency for Science, Technology and Research (ASTAR) Singapore Singapore.
  • Chew E; Division of Neurology, Department of Medicine National University Hospital Singapore Singapore.
  • Henry CJ; Division of Neurology, Department of Medicine National University Hospital Singapore Singapore.
  • Koo E; Department of Medicine, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
  • Chen C; Clinical Nutrition Research Centre Singapore Institute for Clinical Sciences Agency for Science, Technology and Research (ASTAR) Singapore Singapore.
Alzheimers Dement (N Y) ; 7(1): e12141, 2021.
Article in English | MEDLINE | ID: covidwho-1669647
Semantic information from SemMedBD (by NLM)
1. Exercise TREATS risk factors
Subject
Exercise
Predicate
TREATS
Object
risk factors
2. Exercise TREATS risk factors
Subject
Exercise
Predicate
TREATS
Object
risk factors
ABSTRACT

INTRODUCTION:

The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi-domain lifestyle interventions compared to Singaporean adaptations.

METHODS:

Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months.

RESULTS:

Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (Pupper body = .04, P lower body = .06, P core = .05). More participants in the SINGER group attained good blood pressure control at month-6 compared to FINGER (41% vs 19%; P = .06).

DISCUSSION:

This study is the first to compare the feasibility of multi-domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi-domain lifestyle interventions in preventing cognitive decline.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Controlled clinical trial / Randomized controlled trials / Risk factors Language: English Journal: Alzheimers Dement (N Y) Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Controlled clinical trial / Randomized controlled trials / Risk factors Language: English Journal: Alzheimers Dement (N Y) Year: 2021 Document Type: Article