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SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)-pilot: A feasibility study.
Chew, Kimberly Ann; Xu, Xin; Siongco, Paula; Villaraza, Steven; Phua, April Ka Sin; Wong, Zi Xuen; Chung, Chooi Yu; Tang, Ning; Chew, Effie; Henry, Christiani Jeyakumar; Koo, Edward; Chen, Christopher.
  • Chew KA; Memory, Ageing and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
  • Xu X; Memory, Ageing and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
  • Siongco P; School of Public Health and the 2nd Affiliated Hospital of School of Medicine Zhejiang University Hangzhou China.
  • Villaraza S; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Phua AKS; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Wong ZX; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Chung CY; Memory, Ageing and Cognition Centre (MACC), Department of Psychological Medicine National University Hospital Singapore Singapore.
  • Tang N; Clinical Nutrition Research Centre Singapore Institute for Clinical Sciences Agency for Science, Technology and Research (ASTAR) Singapore Singapore.
  • Chew E; Division of Neurology, Department of Medicine National University Hospital Singapore Singapore.
  • Henry CJ; Division of Neurology, Department of Medicine National University Hospital Singapore Singapore.
  • Koo E; Department of Medicine, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
  • Chen C; Clinical Nutrition Research Centre Singapore Institute for Clinical Sciences Agency for Science, Technology and Research (ASTAR) Singapore Singapore.
Alzheimers Dement (N Y) ; 7(1): e12141, 2021.
Article in English | MEDLINE | ID: covidwho-1669647
ABSTRACT

INTRODUCTION:

The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi-domain lifestyle interventions compared to Singaporean adaptations.

METHODS:

Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months.

RESULTS:

Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (Pupper body = .04, P lower body = .06, P core = .05). More participants in the SINGER group attained good blood pressure control at month-6 compared to FINGER (41% vs 19%; P = .06).

DISCUSSION:

This study is the first to compare the feasibility of multi-domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi-domain lifestyle interventions in preventing cognitive decline.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Alzheimers Dement (N Y) Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Alzheimers Dement (N Y) Year: 2021 Document Type: Article