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Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Among Skilled Nursing Facility Residents and Staff Members-Los Angeles County, August-September 2020.
Malenfant, Jason H; Eslami, Michelle; Dao, Bonnie L; Moore, Leo; Green, Nicole; Silver, David; OYong, Kelsey; Ruparelia, Ashutosh; Fisher, Rebecca; Wood, Julia S; Faisal, Mohammad; Washburn, Faith; Shvartsblat, Steve; Jewell, Mirna P; Romo, Tiffany; Foo, Chelsea; Salazar, Angela; Aguirre, Suzette; Balter, Sharon; Bhaurla, Sandeep; Buenrrostro, Sandra; Bui, Kim; Cho, Karen Young; Chun, Katie; Civen, Rachel; Clarke, Anthony; Danza, Phoebe; Fernandes, Priyanka; Fountas, Nicole; Gambon, Marie; Gragnani, Candace M; Griffin, Amber; Guerra, Lidia; Guerrero, Annette; Hooshmand, Kay; Claire Jarashow, M; Knight, Wendy; Kuo, Alice A; Ngo, Thoa; Nunez, Denise M; Obara, Aya; Rawson, Katherine; Terashita, Dawn; Rajagopalan, Shobita; Rubin, Zachary A; Gounder, Prabhu.
  • Malenfant JH; David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
  • Eslami M; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Dao BL; Rockport Healthcare Services, Los Angeles, California, USA.
  • Moore L; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Green N; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Silver D; Public Health Laboratory, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • OYong K; Rockport Healthcare Services, Los Angeles, California, USA.
  • Ruparelia A; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Fisher R; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Wood JS; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Faisal M; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Washburn F; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Shvartsblat S; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Jewell MP; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Romo T; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Foo C; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Salazar A; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Aguirre S; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Balter S; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Bhaurla S; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Buenrrostro S; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Bui K; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Cho KY; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Chun K; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Civen R; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Clarke A; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Danza P; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Fernandes P; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Fountas N; David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
  • Gambon M; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Gragnani CM; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Griffin A; David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
  • Guerra L; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Guerrero A; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Hooshmand K; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Claire Jarashow M; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Knight W; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Kuo AA; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Ngo T; David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
  • Nunez DM; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Obara A; David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
  • Rawson K; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Terashita D; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Rajagopalan S; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Rubin ZA; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
  • Gounder P; Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA.
J Infect Dis ; 225(3): 367-373, 2022 02 01.
Article in English | MEDLINE | ID: covidwho-1672201
ABSTRACT

BACKGROUND:

The prevalence of current or past coronavirus disease 2019 in skilled nursing facility (SNF) residents is unknown because of asymptomatic infection and constrained testing capacity early in the pandemic. We conducted a seroprevalence survey to determine a more comprehensive prevalence of past coronavirus disease 2019 in Los Angeles County SNF residents and staff members.

METHODS:

We recruited participants from 24 facilities; participants were requested to submit a nasopharyngeal swab sample for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) testing and a serum sample for detection of SARS-CoV-2 antibodies. All participants were cross-referenced with our surveillance database to identify persons with prior positive SARS-CoV-2 results.

RESULTS:

From 18 August to 24 September 2020, we enrolled 3305 participants (1340 residents and 1965 staff members). Among 856 residents providing serum samples, 362 (42%) had current or past SARS-CoV-2 infection. Of the 346 serology-positive residents, 199 (58%) did not have a documented prior positive SARS-CoV-2 PCR result. Among 1806 staff members providing serum, 454 (25%) had current or past SARS-CoV-2 infection. Of the 447 serology-positive staff members, 353 (79%) did not have a documented prior positive SARS-CoV-2 PCR result.

CONCLUSIONS:

Past testing practices and policies missed a substantial number of SARS-CoV-2 infections in SNF residents and staff members.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: North America Language: English Journal: J Infect Dis Year: 2022 Document Type: Article Affiliation country: Infdis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: North America Language: English Journal: J Infect Dis Year: 2022 Document Type: Article Affiliation country: Infdis