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Methicillin-resistant Staphylococcus aureus lung infection in coronavirus disease 2019: how common?
Bassetti, Matteo; Magnasco, Laura; Vena, Antonio; Portunato, Federica; Giacobbe, Daniele Roberto.
  • Bassetti M; Infectious Diseases Unit, San Martino Policlinico Hospital - IRCCS.
  • Magnasco L; Department of Health Sciences, University of Genoa, Genoa, Italy.
  • Vena A; Infectious Diseases Unit, San Martino Policlinico Hospital - IRCCS.
  • Portunato F; Infectious Diseases Unit, San Martino Policlinico Hospital - IRCCS.
  • Giacobbe DR; Department of Health Sciences, University of Genoa, Genoa, Italy.
Curr Opin Infect Dis ; 35(2): 149-162, 2022 04 01.
Article in English | MEDLINE | ID: covidwho-1672443
ABSTRACT
PURPOSE OF REVIEW Some patients with coronavirus disease 2019 (COVID-19) may develop pulmonary bacterial coinfection or superinfection, that could unfavorably impact their prognosis. RECENT

FINDINGS:

The exact burden of methicillin-resistant Staphylococcus aureus (MRSA) lung infection in peculiar populations such as patients with COVID-19 remains somewhat elusive, possibly because of wide heterogeneity in methods and endpoints across studies.

SUMMARY:

There was important heterogeneity in the retrieved literature on the epidemiology of MRSA lung infection in patients with COVID-19, both when considering all other bacteria as the denominator (relative prevalence ranging from 2% to 29%) and when considering only S. aureus as the denominator (relative prevalence ranging from 11% to 65%). Overall, MRSA is among the most frequent causative agents of pulmonary infection in patients with COVID-19. Improving our ability to rapidly reach etiological diagnosis of bacterial lung infection in COVID-19 patients remains fundamental if we are to improve the rates of appropriate antibiotic therapy in patients with COVID-19 and concomitant/superimposed MRSA infection, at the same time avoiding antibiotic overuse in line with antimicrobial stewardship principles.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Staphylococcal Infections / Methicillin-Resistant Staphylococcus aureus / COVID-19 Type of study: Prognostic study / Risk factors Topics: Long Covid Limits: Humans Language: English Journal: Curr Opin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Staphylococcal Infections / Methicillin-Resistant Staphylococcus aureus / COVID-19 Type of study: Prognostic study / Risk factors Topics: Long Covid Limits: Humans Language: English Journal: Curr Opin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article