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Relationship Between Blood Lipid Levels and Mortality in Hospitalized COVID-19 Patients.
Aydin, Sidar S; Aksakal, Emrah; Aydinyilmaz, Faruk; Gülcü, Oktay; Saraç, Ibrahim; Kalkan, Kamuran; Aydemir, Selim; Dogan, Remziye; Aksu, Ugur; Tanboga, Ibrahim H.
  • Aydin SS; Department of Cardiology, Dogubeyazit State Hospital, Agri, Turkey.
  • Aksakal E; Department of Cardiology, University of Health Sciences, Erzurum Education and Research Hospital, Erzurum, Turkey.
  • Aydinyilmaz F; Department of Cardiology, University of Health Sciences, Erzurum Education and Research Hospital, Erzurum, Turkey.
  • Gülcü O; Department of Cardiology, University of Health Sciences, Erzurum Education and Research Hospital, Erzurum, Turkey.
  • Saraç I; Department of Cardiology, University of Health Sciences, Erzurum Education and Research Hospital, Erzurum, Turkey.
  • Kalkan K; Department of Cardiology, University of Health Sciences, Erzurum Education and Research Hospital, Erzurum, Turkey.
  • Aydemir S; Department of Cardiology, Maresal Çakmak State Hospital, Erzurum, Turkey.
  • Dogan R; Department of Cardiology, Düzce State Hospital, Düzce, Turkey.
  • Aksu U; Department of Cardiology, 563947Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
  • Tanboga IH; Department of Cardiology, Nisantasi University, 599103Hisar Intercontinental Hospital, Istanbul, Turkey.
Angiology ; 73(8): 724-733, 2022 09.
Article in English | MEDLINE | ID: covidwho-1673644
ABSTRACT
People with comorbid conditions are at increased risk of developing severe/fatal coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between lipid levels and mortality in patients hospitalized for COVID-19 infection. In this retrospective study, we collected the details of 5274 COVID-19 patients who were diagnosed using the polymerase chain reaction and/or computed tomography and were hospitalized between March and November 2020. Patients (n = 4118) whose blood lipid levels were checked within the first 24 h after hospitalization were included in the study. Multivariable cox proportional hazards regression was used to assess the relationship between lipid variables such as low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) and death. There was a statistically significant association between LDL-C, HDL-C, and TG levels and the risk of death (P =.002, <.001, and .035, respectively). Low and high LDL-C, low HDL-C, and high TG levels were negatively associated with COVID-19-related mortality. Blood lipid levels may be useful predictors of mortality in COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Angiology Year: 2022 Document Type: Article Affiliation country: 00033197211072346

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Angiology Year: 2022 Document Type: Article Affiliation country: 00033197211072346