Lung Ultrasound Signs and Their Correlation With Clinical Symptoms in COVID-19 Pregnant Women: The "PINK-CO" Observational Study.
Front Med (Lausanne)
; 8: 768261, 2021.
Article
in English
| MEDLINE | ID: covidwho-1674347
ABSTRACT
OBJECTIVE:
To analyze the application of lung ultrasound (LUS) diagnostic approach in obstetric patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and compare LUS score and symptoms of the patients.DESIGN:
A single-center observational retrospective study from October 31, 2020 to March 31, 2021.SETTING:
Department of Ob/Gyn at the University-Hospital of Udine, Italy.PARTICIPANTS:
Pregnant women with SARS-CoV-2 diagnosed with reverse transcription-PCR (RT-PCR) swab test were subdivided as symptomatic and asymptomatic patients with COVID-19. EXPOSURE Lung ultrasound evaluation both through initial evaluation upon admission and through serial evaluations. MAINOUTCOME:
Reporting LUS findings and LUS score characteristics.RESULTS:
Symptomatic patients with COVID-19 showed a higher LUS (median 3.5 vs. 0, p < 0.001). LUS was significantly correlated with COVID-19 biomarkers as C-reactive protein (CPR; p = 0.011), interleukin-6 (p = 0.013), and pro-adrenomedullin (p = 0.02), and inversely related to arterial oxygen saturation (p = 0.004). The most frequent ultrasound findings were focal B lines (14 vs. 2) and the light beam (9 vs. 0).CONCLUSION:
Lung ultrasound can help to manage pregnant women with SARS-CoV-2 infection during a pandemic surge. STUDY REGISTRATION ClinicalTrials.gov, NCT04823234. Registered on March 29, 2021.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Language:
English
Journal:
Front Med (Lausanne)
Year:
2021
Document Type:
Article
Affiliation country:
Fmed.2021.768261
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