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Antiviral Activities of Algal-Based Sulfated Polysaccharides.
Panggabean, Jonathan Ardhianto; Adiguna, Sya'ban Putra; Rahmawati, Siti Irma; Ahmadi, Peni; Zainuddin, Elmi Nurhaidah; Bayu, Asep; Putra, Masteria Yunovilsa.
  • Panggabean JA; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Bulaksumur, Yogyakarta 55281, Indonesia.
  • Adiguna SP; Research Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jalan Raya Jakarta-Bogor KM. 46, Cibinong 16911, Indonesia.
  • Rahmawati SI; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Bulaksumur, Yogyakarta 55281, Indonesia.
  • Ahmadi P; Research Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jalan Raya Jakarta-Bogor KM. 46, Cibinong 16911, Indonesia.
  • Zainuddin EN; Research Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jalan Raya Jakarta-Bogor KM. 46, Cibinong 16911, Indonesia.
  • Bayu A; Research Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jalan Raya Jakarta-Bogor KM. 46, Cibinong 16911, Indonesia.
  • Putra MY; Faculty of Marine Science and Fisheries, Hasanuddin University, Makassar 90245, Indonesia.
Molecules ; 27(4)2022 Feb 09.
Article in English | MEDLINE | ID: covidwho-1674739
ABSTRACT
An antiviral agent is urgently needed based on the high probability of the emergence and re-emergence of future viral disease, highlighted by the recent global COVID-19 pandemic. The emergence may be seen in the discovery of the Alpha, Beta, Gamma, Delta, and recently discovered Omicron variants of SARS-CoV-2. The need for strategies besides testing and isolation, social distancing, and vaccine development is clear. One of the strategies includes searching for an antiviral agent that provides effective results without toxicity, which is well-presented by significant results for carrageenan nasal spray in providing efficacy against human coronavirus-infected patients. As the primary producer of sulfated polysaccharides, marine plants, including macro- and microalgae, offer versatility in culture, production, and post-isolation development in obtaining the needed antiviral agent. Therefore, this review will describe an attempt to highlight the search for practical and safe antiviral agents from algal-based sulfated polysaccharides and to unveil their features for future development.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Polysaccharides / Microalgae / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Vaccines / Variants Limits: Humans Language: English Journal subject: Biology Year: 2022 Document Type: Article Affiliation country: Molecules27041178

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Polysaccharides / Microalgae / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Vaccines / Variants Limits: Humans Language: English Journal subject: Biology Year: 2022 Document Type: Article Affiliation country: Molecules27041178