The Cognitive Online Self-Test Amsterdam (COST-A): Establishing norm scores in a community-dwelling population.
Alzheimers Dement (Amst)
; 13(1): e12234, 2021.
Article
in English
| MEDLINE | ID: covidwho-1680312
ABSTRACT
BACKGROUND:
Heightened public awareness about Alzheimer's disease and dementia increases the need for at-home cognitive self-testing. We offered Cognitive Online Self-Test Amsterdam (COST-A) to independent groups of cognitively normal adults and investigated the robustness of a norm-score formula and cutoff.METHODS:
Three thousand eighty-eight participants (mean age ± standard deviation = 61 ± 12 years, 70% female) completed COST-A and evaluated it. Demographically adjusted norm scores were the difference between expected COST-A scores, based on age, gender, and education, and actual scores. We applied the resulting norm-score formula to two independent cohorts.RESULTS:
Participants evaluated COST-A to be of adequate difficulty and duration. Our norm-score formula was shown to be robust ≈8% of participants in two cognitively normal cohorts had abnormal scores. A cutoff of -1.5 standard deviations proved optimal for distinguishing normal from impaired cognition.CONCLUSION:
With robust norm scores, COST-A is a promising new tool for research and clinical practice, providing low cost and minimally invasive remote assessment of cognitive functioning.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Language:
English
Journal:
Alzheimers Dement (Amst)
Year:
2021
Document Type:
Article
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