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Prevention and Treatment of SARS-CoV2 Infection in People Living with HIV: The Need for Specific Data.
Díaz, Natalia A; de Miguel, Rosa; Agüero, Fernando; Sued, Omar; Arribas, José R; Ambrosioni, Juan.
  • Díaz NA; Infectious Diseases Service, Hospital Cuenca Alta, Cañuelas, Argentina.
  • de Miguel R; Infectious Diseases Unit, Hospital Universitario La Paz, Madrid, Spain.
  • Agüero F; Preventive Medicine Service, Hospital Universitario Bellvitge, Barcelona, Spain.
  • Sued O; Fundación Huésped, Buenos Aires, Argentina.
  • Arribas JR; Infectious Diseases Unit, Hospital Universitario La Paz, Madrid, Spain.
  • Ambrosioni J; HIV Unit and Infectious Diseases Service, Hospital Clinic-IDIBAPS, Villarroel 170, 08036, Barcelona, Spain. ambrosioni@clinic.cat.
Infect Dis Ther ; 11(1): 1-13, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1682186
ABSTRACT
The HIV pandemic has led to close to 40 million people living with HIV (PLWH) worldwide. To date, SARS-CoV2 has affected > 220 million people, and unprecedented global efforts have resulted in almost 6000 million doses of SARS-CoV2 vaccines being administered. Although several specific COVID-19 antiviral and anti-inflammatory treatments and SARS-CoV2 vaccines have been approved, the data available to support their use in specific populations such as PLWH remain limited. PLWH includes a range of individuals from practically unaffected immunity to severely immunocompromised individuals, and preventive and therapeutic interventions should be tailored for these subgroups . However, in most randomized clinical trials regarding antivirals, immunomodulators and vaccines for COVID-19, PLWH have been excluded or only enrolled in small numbers leading to a paucity of data. We briefly discuss the current evidence for prevention and treatment of COVID-19 in PLWH and identify key areas where more information is required.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Topics: Vaccines Language: English Journal: Infect Dis Ther Year: 2022 Document Type: Article Affiliation country: S40121-021-00547-y

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Topics: Vaccines Language: English Journal: Infect Dis Ther Year: 2022 Document Type: Article Affiliation country: S40121-021-00547-y