aPDT for oral decontamination of hospitalized patients with COVID 19.
Photodiagnosis Photodyn Ther
; 38: 102762, 2022 Jun.
Article
in English
| MEDLINE | ID: covidwho-1683501
ABSTRACT
Emerging variants of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) may have an impact on the virus's transmissibility and pathogenicity and an increased risk of reinfection. Antimicrobial photodynamic therapy (aPDT) is a promising technique to decontaminate the oral cavity to minimize and inactivate microorganisms' load. This article reports through a case series, a proposal for efficient oral decontamination for hospitalized patients with COVID 19 using aPDT. Samples of oral tissues were obtained after aPDT and analyzed using two methods of RT-qPCR to elucidate qualitative and quantitative viral profiles of SARS-CoV-2 RNA in the oral cavity. There was a reduction of viral load in the oral cavity immediately or one hour after the use of aPDT. This method could be a good option to decontaminate the oral cavity to minimize and inactivate microorganism load.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Photochemotherapy
/
COVID-19
Type of study:
Prognostic study
/
Qualitative research
Topics:
Variants
Limits:
Humans
Language:
English
Journal:
Photodiagnosis Photodyn Ther
Journal subject:
Diagnostic Imaging
/
Therapeutics
Year:
2022
Document Type:
Article
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