Your browser doesn't support javascript.
Health-related quality of life in older patients surviving ICU treatment for COVID-19: results from an international observational study of patients older than 70 years.
Soliman, Ivo W; Leaver, Susannah; Flaatten, Hans; Fjølner, Jesper; Wernly, Bernhard; Bruno, Raphael R; Artigas, Antonio; Bollen Pinto, Bernardo; Schefold, Joerg C; Beil, Michael; Sviri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Wollborn, Jakob; Banzo, Maria Jose Arche; Fuest, Kristina; Marsh, Brian; Andersen, Finn H; Moreno, Rui; Boumendil, Ariane; Guidet, Bertrand; Jung, Christian; De Lange, Dylan W.
  • Soliman IW; Department of Intensive Care Medicine, University Medical Center, University of Utrecht, Utrecht, the Netherlands.
  • Leaver S; General Intensive Care, St George's University Hospitals NHS Foundation Trust, London, UK.
  • Flaatten H; Department of Clinical Medicine, University of Bergen, Department of Anaestesia and Intensive Care, Haukeland University Hospital, Bergen, Norway.
  • Fjølner J; Department of Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
  • Wernly B; Department of Anaesthesiology, Perioperative Medicine and Intensive Care Medicine Paracelsus Medical University of Salzburg, Salzburg, Austria.
  • Bruno RR; Division of Cardiology, Pulmonology, and Vascular Medicine, University Duesseldorf, Duesseldorf, Germany.
  • Artigas A; Department of Intensive Care Medicine, CIBER Enfermedades Respiratorias, Corporacion Sanitaria Universitaria Parc Tauli, Autonomous University of Barcelona, Sabadell, Spain.
  • Bollen Pinto B; Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland.
  • Schefold JC; Department of Intensive Care Medicine, Inselspital, Universitätsspital, University of Bern, Bern, Switzerland.
  • Beil M; Department of Medical Intensive Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
  • Sviri S; Department of Medical Intensive Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
  • van Heerden PV; General Intensive Care Unit, Department of Anesthesiology, Critical Care and Pain Medicine, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
  • Szczeklik W; Center for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
  • Elhadi M; Faculty of Medicine, University of Tripoli, Tripoli, Libya.
  • Joannidis M; Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.
  • Oeyen S; Department of Intensive Care 1K12IC, Ghent University Hospital, Ghent, Belgium.
  • Zafeiridis T; Intensive Care Unit, General Hospital of Larissa, Larissa, Greece.
  • Wollborn J; Department of Anesthesiolgy, Perioperative and Pain Medicine, Brigham and Women's Hospital, Havard Medical School, Boston, MA, USA.
  • Banzo MJA; Servicio de Medicina Intensiva, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
  • Fuest K; Department of Anesthesiology and Intensive Care, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.
  • Marsh B; Department of Anesthesia and Intensive Care Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.
  • Andersen FH; Department of Anaesthesia and Intensive Care, Ålesund Hospital, Ålesund, Norway.
  • Moreno R; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
  • Boumendil A; Unidade de Cuidados Intensivos Neurocríticos e Trauma. Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Faculdade de Ciências Médicas de Lisboa, Nova Médical School, Lisbon, Portugal.
  • Guidet B; Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe: épidémiologie hospitalière qualité et organisation des soins, F-75012 Paris, France.
  • Jung C; Assistance Publique - Hôpitaux de Paris, Hôpital Saint-Antoine, service de réanimation médicale, F-75012 Paris, France.
  • De Lange DW; Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe: épidémiologie hospitalière qualité et organisation des soins, F-75012 Paris, France.
Age Ageing ; 51(2)2022 02 02.
Article in English | MEDLINE | ID: covidwho-1684499
ABSTRACT

BACKGROUND:

health-related quality of life (HRQoL) is an important patient-centred outcome in patients surviving ICU admission for COVID-19. It is currently not clear which domains of the HRQoL are most affected.

OBJECTIVE:

to quantify HRQoL in order to identify areas of interventions.

DESIGN:

prospective observation study.

SETTING:

admissions to European ICUs between March 2020 and February 2021.

SUBJECTS:

patients aged 70 years or older admitted with COVID-19 disease.

METHODS:

collected determinants include SOFA-score, Clinical Frailty Scale (CFS), number and timing of ICU procedures and limitation of care, Katz Activities of Daily Living (ADL) dependence score. HRQoL was assessed at 3 months after ICU admission with the Euro-QoL-5D-5L questionnaire. An outcome of ≥4 on any of Euro-QoL-5D-5L domains was considered unfavourable.

RESULTS:

in total 3,140 patients from 14 European countries were included in this study. Three months after inclusion, 1,224 patients (39.0%) were alive and the EQ-5D-5L from was obtained. The CFS was associated with an increased odds ratio for an unfavourable HRQoL outcome after 3 months; OR 1.15 (95% confidence interval (CI) 0.71-1.87) for CFS 2 to OR 4.33 (95% CI 1.57-11.9) for CFS ≧ 7. The Katz ADL was not statistically significantly associated with HRQoL after 3 months.

CONCLUSIONS:

in critically ill old intensive care patients suffering from COVID-19, the CFS is associated with the subjectively perceived quality of life. The CFS on admission can be used to inform patients and relatives on the risk of an unfavourable qualitative outcome if such patients survive.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Quality of Life / COVID-19 Type of study: Cohort study / Observational study / Prognostic study / Qualitative research Limits: Aged / Humans Language: English Year: 2022 Document Type: Article Affiliation country: Ageing

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Quality of Life / COVID-19 Type of study: Cohort study / Observational study / Prognostic study / Qualitative research Limits: Aged / Humans Language: English Year: 2022 Document Type: Article Affiliation country: Ageing