Your browser doesn't support javascript.
SARS-CoV-2 infection fatality rate after the first epidemic wave in Mexico.
Torres-Ibarra, Leticia; Basto-Abreu, Ana; Carnalla, Martha; Torres-Alvarez, Rossana; Reyes-Sanchez, Francisco; Hernández-Ávila, Juan E; Palacio-Mejia, Lina S; Alpuche-Aranda, Celia; Shamah-Levy, Teresa; Rivera, Juan A; Barrientos-Gutierrez, Tonatiuh.
  • Torres-Ibarra L; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico.
  • Basto-Abreu A; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico.
  • Carnalla M; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico.
  • Torres-Alvarez R; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico.
  • Reyes-Sanchez F; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico.
  • Hernández-Ávila JE; Center for Research in Evaluation and Surveys, National Institute of Public Health, Cuernavaca, Mexico.
  • Palacio-Mejia LS; CONACYT-Instituto Nacional de Salud Pública, Cuernavaca, Mexico.
  • Alpuche-Aranda C; Center for Research on Infectious Diseases, National Institute of Public Health, Cuernavaca, Mexico.
  • Shamah-Levy T; Center for Research in Evaluation and Surveys, National Institute of Public Health, Cuernavaca, Mexico.
  • Rivera JA; General Director, National Institute of Public Health, Cuernavaca, Mexico.
  • Barrientos-Gutierrez T; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico.
Int J Epidemiol ; 51(2): 429-439, 2022 05 09.
Article in English | MEDLINE | ID: covidwho-1684698
ABSTRACT

BACKGROUND:

Estimates of SARS-CoV-2 infection fatality rates (IFRs) in developing countries remain poorly characterized. Mexico has one of the highest reported COVID-19 case-fatality rates worldwide, although available estimates do not consider serologic assessment of prior exposure nor all SARS-CoV-2-related deaths. We aimed to estimate sex- and age-specific IFRs for SARS-CoV-2 in Mexico.

METHODS:

The total number of people in Mexico with evidence of prior SARS-CoV-2 infection was derived from National Survey of Health and Nutrition-COVID-19 (ENSANUT 2020 Covid-19)-a nationally representative serosurvey conducted from August to November 2020. COVID-19 mortality data matched to ENSANUT's dates were retrieved from the death-certificate registry, which captures the majority of COVID-19 deaths in Mexico, and from the national surveillance system, which covers the subset of COVID-19 deaths that were identified by the health system and were confirmed through a positive polymerase chain reaction test. We analysed differences in IFRs by urbanization and region.

RESULTS:

The national SARS-CoV-2 IFR was 0.47% (95% CI 0.44, 0.50) using death certificates and 0.30% (95% CI 0.28, 0.33) using surveillance-based deaths. The IFR increased with age, being close to zero at age <30 years, but increasing to 1% at ages 50-59 years in men and 60-69 years in women, and being the highest at ≥80 years for men (5.88%) and women (6.23%). Across Mexico's nine regions, Mexico City (0.99%) had the highest and the Peninsula (0.26%) the lowest certificate-based IFRs. Metropolitan areas had higher certificate-based IFR (0.63%) than rural areas (0.17%).

CONCLUSION:

After the first wave of the COVID-19 pandemic, the overall IFR in Mexico was comparable with those of European countries. The IFR in Mexico increased with age and was higher in men than in women. The variations in IFRs across regions and places of residence within the country suggest that structural factors related to population characteristics, pandemic containment and healthcare capabilities could have influenced lethality at the local level.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Mexico Language: English Journal: Int J Epidemiol Year: 2022 Document Type: Article Affiliation country: Ije

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Mexico Language: English Journal: Int J Epidemiol Year: 2022 Document Type: Article Affiliation country: Ije