Intrahepatic cholestasis of pregnancy resistant to both therapeutic plasma exchange and albumin dialysis.
BMJ Case Rep
; 15(2)2022 Feb 08.
Article
in English
| MEDLINE | ID: covidwho-1685516
ABSTRACT
Intrahepatic cholestasis in pregnancy (ICP) represents, depending on its severity, a serious risk for the fetus. Those cases with unusually high bile acid levels may be resistant to pharmaceutical treatment and can be treated with plasma exchange or albumin dialysis. However, the success rate of these therapeutic options and the factors influencing therapeutic response are unknown. Furthermore, if these options fail to improve ICP and serum bile acid levels are very high (>200 µm/L), there are no clear recommendations when delivery should be planned. Here, we report a patient with severe ICP resistant to both therapeutic plasma exchange and albumin dialysis. Caesarean section was performed at 32 weeks of gestation followed by rapid remission of ICP.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pregnancy Complications
/
Cholestasis, Intrahepatic
Type of study:
Case report
/
Prognostic study
Limits:
Female
/
Humans
/
Pregnancy
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Bcr-2021-246318
Similar
MEDLINE
...
LILACS
LIS