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Learning through a Pandemic: The Current State of Knowledge on COVID-19 and Cancer.
Elkrief, Arielle; Wu, Julie T; Jani, Chinmay; Enriquez, Kyle T; Glover, Michael; Shah, Mansi R; Shaikh, Hira Ghazal; Beeghly-Fadiel, Alicia; French, Benjamin; Jhawar, Sachin R; Johnson, Douglas B; McKay, Rana R; Rivera, Donna R; Reuben, Daniel Y; Shah, Surbhi; Tinianov, Stacey L; Vinh, Donald Cuong; Mishra, Sanjay; Warner, Jeremy L.
  • Elkrief A; Division of Medical Oncology (Department of Medicine), McGill University Health Centre, Montreal, Quebec, Canada.
  • Wu JT; Stanford University, Palo Alto, California.
  • Jani C; Mount Auburn Hospital, Harvard Medical School, Cambridge, Massachusetts.
  • Enriquez KT; Vanderbilt University School of Medicine, Nashville, Tennessee.
  • Glover M; Stanford University, Palo Alto, California.
  • Shah MR; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
  • Shaikh HG; University of Cincinnati Cancer Center, Cincinnati, Ohio.
  • Beeghly-Fadiel A; Vanderbilt University Medical Center, Nashville, Tennessee.
  • French B; Vanderbilt University Medical Center, Nashville, Tennessee.
  • Jhawar SR; The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.
  • Johnson DB; Vanderbilt University Medical Center, Nashville, Tennessee.
  • McKay RR; University of California San Diego, San Diego, California.
  • Rivera DR; Division of Cancer Control and Population Services, National Cancer Institute, Rockville, Maryland.
  • Reuben DY; Medical University of South Carolina, Charleston, South Carolina.
  • Shah S; Hematology and Oncology, Mayo Clinic Arizona, Phoenix, Arizona.
  • Tinianov SL; Advocates for Collaborative Education, UCSF Breast Science Advocacy Core, San Francisco, California.
  • Vinh DC; Division of Infectious Diseases (Department of Medicine), Divisions of Medical Microbiology and of Molecular Diagnostics (OptiLab), McGill University Health Centre, Montreal, Quebec, Canada.
  • Mishra S; Vanderbilt University Medical Center, Nashville, Tennessee.
  • Warner JL; Vanderbilt University Medical Center, Nashville, Tennessee. jeremy.warner@vumc.org.
Cancer Discov ; 12(2): 303-330, 2022 02.
Article in English | MEDLINE | ID: covidwho-1685769
ABSTRACT
The ongoing coronavirus disease 2019 (COVID-19) pandemic has left patients with current or past history of cancer facing disparate consequences at every stage of the cancer trajectory. This comprehensive review offers a landscape analysis of the current state of the literature on COVID-19 and cancer, including the immune response to COVID-19, risk factors for severe disease, and impact of anticancer therapies. We also review the latest data on treatment of COVID-19 and vaccination safety and efficacy in patients with cancer, as well as the impact of the pandemic on cancer care, including the urgent need for rapid evidence generation and real-world study designs.

SIGNIFICANCE:

Patients with cancer have faced severe consequences at every stage of the cancer journey due to the COVID-19 pandemic. This comprehensive review offers a landscape analysis of the current state of the field regarding COVID-19 and cancer. We cover the immune response, risk factors for severe disease, and implications for vaccination in patients with cancer, as well as the impact of the COVID-19 pandemic on cancer care delivery. Overall, this review provides an in-depth summary of the key issues facing patients with cancer during this unprecedented health crisis.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Neoplasms Type of study: Observational study / Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Cancer Discov Year: 2022 Document Type: Article Affiliation country: 2159-8290.CD-21-1368

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Neoplasms Type of study: Observational study / Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Cancer Discov Year: 2022 Document Type: Article Affiliation country: 2159-8290.CD-21-1368