Enhancement of Bacterial Anti-Adhesion Properties on Robust PDMS Micro-Structure Using a Simple Flame Treatment Method.

ABSTRACT

Biofilm-associated infections caused by an accumulation of micro-organisms and pathogens significantly impact the environment, health risks, and the global economy. Currently, a non-biocide-releasing superhydrophobic surface is a potential solution for antibacterial purposes. This research demonstrated a well-designed robust polydimethylsiloxane (PDMS) micro-structure and a flame treatment process with improved hydrophobicity and bacterial anti-adhesion properties. After the flame treatment at 700 ± 20 °C for 15 s, unique flower-petal re-entrant nano-structures were formed on pillars (PIL-F, width 1.87 ± 0.30 µm, height 7.76 ± 0.13 µm, aspect ratio (A.R.) 4.14) and circular rings with eight stripe supporters (C-RESS-F, width 0.50 ± 0.04 µm, height 3.55 ± 0.11 µm, A.R. 7.10) PDMS micro-patterns. The water contact angle (WCA) and ethylene glycol contact angle (EGCA) of flame-treated flat-PDMS (FLT-F), PIL-F, and C-RESS-F patterns were (133.9 ± 3.8°, 128.6 ± 5.3°), (156.1 ± 1.5°, 151.5 ± 2.1°), and (146.3 ± 3.5°, 150.7 ± 1.8°), respectively. The Escherichia coli adhesion on the C-RESS-F micro-pattern with hydrophobicity and superoleophobicity was 42.6%, 31.8%, and 2.9% less than FLT-F, PIL-F, and Teflon surfaces. Therefore, the flame-treated C-RESS-F pattern is one of the promising bacterial anti-adhesion micro-structures in practical utilization for various applications.