PCR performance in the SARS-CoV-2 Omicron variant of concern?
Swiss Med Wkly
; 151: w30120, 2021 12 06.
Article
in English
| MEDLINE | ID: covidwho-1687293
ABSTRACT
The new SARS-CoV-2 Omicron variant (B.1.1.529) has been recently declared a Variant of Concern due to a series of important mutations in the viral spike protein and especially in the receptor-binding domain. While investigations into the spread of this new variant are ongoing, the first cases have been detected in Switzerland. Important questions have been raised (1) Will the PCR assays commonly used to detect SARS-CoV-2 still work for the Omicron variant? (2) Can specific PCR features, e.g. S-gene dropout, be used to identify potential Omicron samples? In this minireview we provide current knowledge on the Omicron variant and guidance on its PCR validation.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Prognostic study
Topics:
Variants
Limits:
Humans
Language:
English
Journal:
Swiss Med Wkly
Journal subject:
Medicine
Year:
2021
Document Type:
Article
Affiliation country:
SMW.2021.w30120
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