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Clinical features of COVID‑19 in patients with prominent digestive symptoms
Medical Journal of Wuhan University ; 43(2):179-183, 2022.
Article in Chinese | Scopus | ID: covidwho-1687523
ABSTRACT

Objective:

To analyze the clinical characteristics of COVID‑19 in the patients with predominant digestive symptoms and to discuss related clinical issues.

Methods:

A retrospective clinical analysis was performed on 638 discharged patients with confirmed COVID‑19 from January 30, 2020 to March 10, 2020, to collect their basic information, first symptoms, laboratory results, nucleic acid test, disease severity, and outcomes.

Results:

Of the 638 patients with COVID‑19, fever was the most common first symptom. There were 87 cases (13.6%) with obvious digestive symptoms and 551 cases (86.4%) without digestive symptoms, of which, diarrhea was the most common (67.8%) one. As compared with those without predominant digestive symptoms, these COVID cases were younger in age, had higher rate of cough (65.5%), higher maximum body temperature, and higher proportion of WBC counts <4.0×109/L. However, patients without gastrointestinal symptoms had a higher level of ultra‑troponin I. There was no significant difference between the two groups in terms of gender composition, fever, sputum, chest pain, chest tightness, dyspnea, and basic diseases. Meanwhile, no statistical difference was found between the two groups in most laboratory results, duration of viral shedding, the production of specific antibodies, characteristics of chest CT imaging, disease severity, and death rate.

Conclusion:

The diarrhea‑mainly digestive symptoms were the first‑episode symptoms in some patients with COVID‑19, their clinical characteristics and the courses were generally similar to those without obvious digestive symptoms. In view of the fact that some patients have positive nucleic acid test on anal swab and there is a risk of gastrointestinal transmission, the clinical care requirements and difficulties have increased for such patients. © 2022, Editorial Board of Medical Journal of Wuhan University. All right reserved.
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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2022 Document Type: Article