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Assessment of pulmonary ventilation function and influencing factors in COVID‑19 patients six months after discharge from hospital
Medical Journal of Wuhan University ; 43(2):184-188, 2022.
Article in Chinese | Scopus | ID: covidwho-1687526
ABSTRACT

Objective:

To assess the level of pulmonary ventilation function in patients with COVID‑19 after six months post⁃discharge and analyze the relevant influencing factors.

Methods:

In November 2020, patients with COVID‑19 were investigated in a district of Wuhan City, Hubei Province. Their pulmonary ventilation function indicators were measured, including forced vital capacity of percent predicted (FVC%pred), forced expiratory volume in one second of percent predicted (FEV1%pred), FEV1/FVC ratio (FEV1/FVC%), forced expiratory flow at 50% of percent predicted (FEF50%pred), forced expiratory flow at 75% of percent predicted (FEF75%pred), mean forced expiratory flow between 25% and 75% of percent predicted (MMEF%pred). The related factors affecting pulmonary ventilation function were analyzed.

Results:

A total of 151 discharged cases were recruited, which included 64 cases of mild illness, 87 cases of moderate illness. The average age of both men and women in the mild group was significantly higher than that in the moderate group (P<0.05). The mean values of the lung ventilation function indexes were all within the normal range. The FVC%pred in both male and female and FEV1%pred in female were better in the mild group than that in the moderate group (P<0.05). Some patients had mild abnormal pulmonary ventilation function and 11 cases in the mild group, 46 cases in the moderate group. Multi‑factor logistic regression analysis showed that women [OR=3.012, 95%CI(1.249,7.264)], the presence of a previous history of chronic disease [OR=2.739, 95%CI(1.186,6.326)], and cases of moderate illness [OR=6.365, 95%CI(2.730,14.840)] were the risk factors for abnormal pulmonary ventilation function after discharge.

Conclusion:

Half a year after discharge, the pulmonary ventilation function of both mild and moderate group patients recovered well. Women and those with chronic disease in the past should have more targeted health guidance during the post‑discharge recovery period. © 2022, Editorial Board of Medical Journal of Wuhan University. All right reserved.
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Full text: Available Collection: Databases of international organizations Database: Scopus Language: Chinese Journal: Medical Journal of Wuhan University Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Language: Chinese Journal: Medical Journal of Wuhan University Year: 2022 Document Type: Article