Pneumomediastinum in COVID-19 Patients with Acute Respiratory Distress Syndrome.
J Nepal Health Res Counc
; 19(3): 460-466, 2021 Dec 10.
Article
in English
| MEDLINE | ID: covidwho-1687865
ABSTRACT
BACKGROUND:
Pneumomediastinum, an uncommon entity, has been on the rise with increasing cases of COVID-Acute respiratory distress syndrome. It has been unclear whether this entity represents an indicator of poor clinical outcome or not. The aims of this study were to find out the incidence of pneumomediastinum in COVID-Acute respiratory distress syndrome patients, describe their clinical characteristics and try to explain its plausible mechanisms..METHODS:
A descriptive, cross-sectional study was carried out in the ICU of our hospital among 280 patients admitted with COVID-Acute respiratory distress syndrome over a period of 6 months. Demographics along with various clinical, laboratory, and radiological parameters were analyzed. Relevant statistical analyses were done to summarize our findings.RESULTS:
The incidence of pneumomediastinum in COVID-ARDS patients was 2.8%. All patients were male, none had pulmonary co-morbidities and six of them (60%) were on invasive mechanical ventilation. All intubated patients were on lung protective mechanical ventilation. The median PEEP, peak airway pressure and plateau pressure were 10 (IQR 4), 29 (IQR 8) and 28 (IQR 4) respectively. The mean CT severity score was 22.7 (SD 1.64). Five patients died after 6.8 days (SD 4.8) of diagnosis. The average hospital stay was of 34 days.CONCLUSIONS:
Pneumomediastinum is a possible complication of COVID-Acute respiratory distress syndrome which could signify the disease severity and vice versa. Furthermore, it could be an indicator of relatively poor prognosis and therefore requires larger studies to establish the association.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Respiratory Distress Syndrome
/
COVID-19
/
Mediastinal Emphysema
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
J Nepal Health Res Counc
Journal subject:
Health Services Research
Year:
2021
Document Type:
Article
Affiliation country:
Jnhrc.v19i3.3612
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