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Poor Antibody Response After Two Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine in Transplant Recipients.
Mazzola, Alessandra; Todesco, Eve; Drouin, Sarah; Hazan, Fanny; Marot, Stéphane; Thabut, Dominique; Varnous, Shaida; Soulié, Cathia; Barrou, Benoît; Marcelin, Anne-Geneviève; Conti, Filomena.
  • Mazzola A; Sorbonne Université, Unité Médicale de Transplantation Hépatique, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Todesco E; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de Virologie, Paris, France.
  • Drouin S; Sorbonne Université, Service Médico-chirugical de Transplantation rénale, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Hazan F; Sorbonne Université, Chirurgie Cardiaque et Thoracique, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Marot S; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de Virologie, Paris, France.
  • Thabut D; Sorbonne Université, Service d'Hépato-gastroentérologie, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Varnous S; Sorbonne Université, Chirurgie Cardiaque et Thoracique, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Soulié C; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de Virologie, Paris, France.
  • Barrou B; Sorbonne Université, Service Médico-chirugical de Transplantation rénale, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Marcelin AG; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de Virologie, Paris, France.
  • Conti F; Sorbonne Université, Unité Médicale de Transplantation Hépatique, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
Clin Infect Dis ; 74(6): 1093-1096, 2022 03 23.
Article in English | MEDLINE | ID: covidwho-1692245
ABSTRACT
A low anti-spike antibody response of 28.6% was observed 28 days after BNT162b2 vaccine second dose among 133 solid organ transplant recipients without previous coronavirus disease 2019 (COVID-19). No serious adverse events were recorded. Four severe COVID-19 cases were reported between or after the 2 doses. Our data suggest to change the vaccine strategy.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid