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Incidence of COVID-19 infection in hospital workers from March 1, 2020 to May 31, 2021 routinely tested, before and after vaccination with BNT162B2.
Larese Filon, Francesca; Rui, Francesca; Ronchese, Federico; De Michieli, Paola; Negro, Corrado.
  • Larese Filon F; Unit of Occupational Medicine, University of Trieste, Via della Pietà 2/2, 34129, Trieste, Italy. larese@units.it.
  • Rui F; Unit of Occupational Medicine, University of Trieste, Via della Pietà 2/2, 34129, Trieste, Italy.
  • Ronchese F; Unit of Occupational Medicine, University of Trieste, Via della Pietà 2/2, 34129, Trieste, Italy.
  • De Michieli P; Unit of Occupational Medicine, University of Trieste, Via della Pietà 2/2, 34129, Trieste, Italy.
  • Negro C; Unit of Occupational Medicine, University of Trieste, Via della Pietà 2/2, 34129, Trieste, Italy.
Sci Rep ; 12(1): 2533, 2022 02 15.
Article in English | MEDLINE | ID: covidwho-1692569
ABSTRACT
To evaluate the incidence of COVID-19 infection in health care workers from the start of the COVID-19 pandemic in NE Italy, vaccination with BNT162b2. This was a retrospective cohort study. Healthcare workers were routinely tested for SARS-CoV-2 infection using real-time polymerase chain reaction tests in nasopharyngeal swabs. Logistic regression was used to calculate the incidence rate ratios (IRRs) of the factors associated with COVID-19. A total of 4251 workers were followed up, and the prevalence of COVID-19 was 13.6%. In March 2021 the incidence of infection was 4.88 and 103.55 cases for 100,000 person-days in vaccinated and non-vaccinated workers, respectively, with an adjusted IRRs of 0.05 (95% CI 0.02-0.08). Our study evaluated the monthly incidence in health care workers in Trieste hospitals before and after vaccination, finding an estimated vaccine effectiveness of 95% in health care workers routinely tested.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Health Personnel / COVID-19 / BNT162 Vaccine Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-021-04665-y

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Health Personnel / COVID-19 / BNT162 Vaccine Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-021-04665-y