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Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in León, Nicaragua.
González, Fredman; Vielot, Nadja A; Sciaudone, Michael; Toval-Ruíz, Christian; Premkumar, Lakshmanane; Gutierrez, Lester; Cuadra, Edwing Centeno; Munguia, Nancy; Blandón, Patricia; de Silva, Aravinda M; Rubinstein, Rebecca; Bowman, Natalie; Becker-Dreps, Sylvia; Bucardo, Filemon.
  • González F; Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
  • Vielot NA; Department of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Sciaudone M; Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Toval-Ruíz C; Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
  • Premkumar L; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Gutierrez L; Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
  • Cuadra EC; Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
  • Munguia N; Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
  • Blandón P; Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
  • de Silva AM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Rubinstein R; School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Bowman N; Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Becker-Dreps S; Department of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Bucardo F; Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
Epidemiol Infect ; 149: e247, 2021 10 20.
Article in English | MEDLINE | ID: covidwho-1692716
ABSTRACT
In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Central America / Nicaragua Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S0950268821002144

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Central America / Nicaragua Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S0950268821002144