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Coincidence or reality behind Mucormycosis, diabetes mellitus and Covid-19 association: A systematic review.
Sengupta, Indraneel; Nayak, Tilak.
  • Sengupta I; Department of Life Science and Biotechnology, Jadavpur University, Kolkata 700032, India.
  • Nayak T; Department of Life Science and Biotechnology, Jadavpur University, Kolkata 700032, India. Electronic address: tnayak078@gmail.com.
J Mycol Med ; 32(3): 101257, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1693081
ABSTRACT
Mucormycosis is a rare but life-threatening disease with high morbidity and mortality and is difficult to diagnose. Mucormycosis, is a severe but rare fungal infection caused by a group of molds called mucormycetes. Diabetes, use of corticosteroids, metabolic/diabetic acidosis and Covid-19 mediated immunosuppression are reported in more than 70% of cases in mucormycosis patients. Coexisting mucormycosis, Covid-19 along with diabetes mellitus increase the likelihood of mortality. Despite its occurrence since the beginning of the pandemic, there are still unanswered concerns regarding the origin of this fungal infection and mortality rate and/or relation with diabetic patients. In this review, we describe the detailed view of causative pathogens responsible for mucormycosis, diabetes mellitus and Covid-19 association along with the morbidity cases during the latest Covid-19 crisis. In the case of mucormycosis diagnosis, imaging, histopathological confirmation, fungal culture and molecular identification methods should be considered. Once mucormycosis is diagnosed, a combined treating method consisting of antifungals administration like amphotericin B, surgical intervention is needed for the reversal of the underlying condition. Early detection of this potentially life-threatening infection and timely care is needed in lowering mortality rates.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetic Ketoacidosis / Diabetes Mellitus / COVID-19 / Mucormycosis Type of study: Diagnostic study / Observational study / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: J Mycol Med Year: 2022 Document Type: Article Affiliation country: J.mycmed.2022.101257

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetic Ketoacidosis / Diabetes Mellitus / COVID-19 / Mucormycosis Type of study: Diagnostic study / Observational study / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: J Mycol Med Year: 2022 Document Type: Article Affiliation country: J.mycmed.2022.101257