Cutaneous reactions to COVID-19 vaccines: A review.
JAAD Int
; 7: 178-186, 2022 Jun.
Article
in English
| MEDLINE | ID: covidwho-1693291
ABSTRACT
Background:
The increasing number of reports on cutaneous reactions following COVID-19 vaccination has led to growing concerns among certain groups.Objective:
We reviewed the published reports of cutaneous lesions after COVID-19 vaccination.Methods:
We conducted a literature search for original and review articles published between January 1, 2020, and September 27, 2021.Results:
Eleven cutaneous reactions associated with COVID-19 vaccines were determined; the most prevalent reactions were local injection site reactions, delayed local reactions, urticaria, angioedema, and morbilliform eruptions. There were more reports on skin reactions following the administration of messenger RNA-based vaccines than on those following the administration of adenoviral vector or inactivated whole-virus vaccines, in part, due to their higher administration rate. Most reported skin reactions occurred after the first vaccine dose.Limitations:
A reporting bias could not be excluded, and skin biopsy results were not available for most included individuals. Moreover, given that the included trials focused on vaccine efficacy, there was a lack of details concerning cutaneous reactions and participant information.Conclusion:
Not all cutaneous reactions observed after COVID-19 vaccination are hypersensitivity reactions. Different cutaneous reactions may reflect underlying immune responses to the vaccines. A large majority of COVID-19 vaccination reactions were mild and self-limiting, and people should be encouraged to complete their vaccination regimen.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
/
Randomized controlled trials
Topics:
Vaccines
Language:
English
Journal:
JAAD Int
Year:
2022
Document Type:
Article
Affiliation country:
J.jdin.2022.01.011
Similar
MEDLINE
...
LILACS
LIS