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Sequential coupling of dry and wet COVID-19 screening to reduce the number of quarantined individuals.
Po Harvey Chin, Yen; Song, Wenyu; Islam, Md Mohaimenul; Bates, David W; Zhou, Li; Chuan Jack Li, Yu.
  • Po Harvey Chin Y; Division of General Internal Medicine & Primary Care, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei, Taiwan.
  • Song W; Division of General Internal Medicine & Primary Care, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
  • Islam MM; Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei, Taiwan.
  • Bates DW; Division of General Internal Medicine & Primary Care, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
  • Zhou L; Division of General Internal Medicine & Primary Care, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
  • Chuan Jack Li Y; Division of General Internal Medicine & Primary Care, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei, Taiwan. Electronic address: jack@tmu.edu.tw.
Comput Methods Programs Biomed ; 218: 106715, 2022 May.
Article in English | MEDLINE | ID: covidwho-1702300
ABSTRACT

INTRODUCTION:

Currently, several countries are facing severe public health and policy challenges when designing their COVID-19 screening strategy. A quantitative analysis of the potential impact that combing the Rapid Antigen Test (RAT; Wet screening) and digital checker (Dry screening) can have on the healthcare system is lacking.

METHOD:

We created a hypothetical COVID-19 cohort for the analysis. The population size was set as 10 million with three levels of disease prevalence (10%, 1%, or 0.1%) under the assumption that a positive test result will lead to quarantine. A digital checker and two RATs are used for analysis. We further hypothesized two scenarios RAT only and RAT plus digital checker. We then calculated the number of quarantined in both scenarios and compared the two to understand the benefits of sequential coupling of a digital checker with a RAT.

RESULT:

Sequential coupling of the digital checker and RAT can significantly reduce the number of individuals quarantined to 0.95-1.33M, 0.86-1.29M, and 0.86-1.29M, respectively, under the three different prevalence levels.

CONCLUSION:

Sequential coupling of digital checker and RAT at a population level for COVID-19 positive test to reduce the number of people who require quarantine and alleviating stress on the overburdened healthcare systems during the COVID-19 pandemic.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Humans Language: English Journal: Comput Methods Programs Biomed Journal subject: Medical Informatics Year: 2022 Document Type: Article Affiliation country: J.cmpb.2022.106715

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Humans Language: English Journal: Comput Methods Programs Biomed Journal subject: Medical Informatics Year: 2022 Document Type: Article Affiliation country: J.cmpb.2022.106715