How the COVID-19 Overcomes the Battle? An Approach to Virus Structure.
Iran J Kidney Dis
; 14(3): 167-172, 2020 05.
Article
in English
| MEDLINE | ID: covidwho-170321
ABSTRACT
Coronaviruses primarily cause zoonotic infections, however in the past few decades several interspecies transmissions have occurred, the last one by SARS-CoV-2, causing COVID-19 pandemic, posing serious threat to global health. The SARS-CoV-2 spike (S) protein plays an important role in viral attachment, fusion and entry. However, other structural and non-structural SARS-CoV-2 proteins are potential influencers in virus pathogenicity. Among these proteins; Orf3, Orf8, and Orf10 show the least homology to SARSCoV proteins and therefore should be further studied for their abilities to modulate antiviral and inflammatory responses. Here, we discuss how SARS-COV-2 interacts with our immune system.
Search on Google
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Viral Proteins
/
Genome, Viral
/
Coronavirus Infections
/
Betacoronavirus
/
Immune System
Limits:
Animals
/
Humans
Language:
English
Journal:
Iran J Kidney Dis
Journal subject:
Nephrology
Year:
2020
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS