Myocarditis and pericarditis following mRNA COVID-19 vaccination in younger patients: is there a shared thread?
Expert Rev Cardiovasc Ther
; 20(2): 87-90, 2022 Feb.
Article
in English
| MEDLINE | ID: covidwho-1703307
ABSTRACT
Rare cases of myocarditis and pericarditis after COVID-19 mRNA vaccination have been recently reported in male adolescents and young adults. Acute myocarditis and pericarditis following COVID-19 mRNA vaccination in male adolescents and young adults may be connected with age-related lower levels of T-bet and PD-1 in predisposed individulas with T-bet polymorphisms by the release od autoreactive CD8+CTL. Upregulatiomn of T-Bet and PD-1 by estrogen might explai the higher incidence of men developing myocarditis or pericarditis in comparison to women.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pericarditis
/
COVID-19
/
Myocarditis
Type of study:
Observational study
Topics:
Long Covid
/
Vaccines
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Young adult
Language:
English
Journal:
Expert Rev Cardiovasc Ther
Journal subject:
Vascular Diseases
/
Cardiology
/
Therapeutics
Year:
2022
Document Type:
Article
Affiliation country:
14779072.2022.2044305
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