Comprehensive review on molnupiravir in COVID-19: a novel promising antiviral to combat the pandemic.
Future Microbiol
; 17: 377-391, 2022 03.
Article
in English
| MEDLINE | ID: covidwho-1704946
ABSTRACT
Despite the progress in the management of COVID-19, effective oral antiviral agents are still lacking. In the present review, the potential beneficial effects of molnupiravir in the management of COVID-19 are discussed. A literature search in Google Scholar, Scopus, PubMed and clinicaltrials.gov for the relevant articles regarding the pharmacokinetics, pharmacodynamics and clinical trials of molnupiravir in the management of COVID-19 is conducted. Most of the preclinical studies and available clinical trials showed a favorable short-term safety profile of molnupiravir; however, given its possible genotoxic effects, further trials are required to confirm the long-term efficacy and safety of molnupiravir in patients with COVID-19.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
COVID-19 Drug Treatment
Type of study:
Prognostic study
/
Reviews
Limits:
Humans
Language:
English
Journal:
Future Microbiol
Journal subject:
Microbiology
Year:
2022
Document Type:
Article
Affiliation country:
Fmb-2021-0252
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